3-(2-bromo-4,5-dimethoxyphenyl)-2-cyanopropionic acid

Base Information

• Chemical Name: 3-(2-bromo-4,5-dimethoxyphenyl)-2-cyanopropionic acid
• CAS No.: 41234-20-2
• Molecular Formula: C₁₂H₁₂BrNO₄
• Molecular Weight: 314.136
• Mol file: 41234-20-2.mol

Synonyms:3-(2-bromo-4,5-dimethoxyphenyl)-2-cyanopropionic acid

Chemical Property of 3-(2-bromo-4,5-dimethoxyphenyl)-2-cyanopropionic acid

Chemical Property:

• Melting Point: 165-167 °C
• Boiling Point: 457.9±45.0 °C(Predicted)
• Density: 1.511±0.06 g/cm3(Predicted)

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(2-bromo-4,5-dimethoxyphenyl)-2-cyanopropionic acid

There total 2 articles about 3-(2-bromo-4,5-dimethoxyphenyl)-2-cyanopropionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

3-(2-bromo-4,5-dimethoxyphenyl)-2-cyanoacrylic acid (41234-19-9) → 3-(2-bromo-4,5-dimethoxyphenyl)-2-cyanopropionic acid (41234-20-2)

Guidance literature:

With sodium tetrahydroborate; sodium hydrogencarbonate; In water; at 20 ℃; for 12h;

DOI:10.3184/030823409X4655259

Reference yield:

→ 3-(2-bromo-4,5-dimethoxyphenyl)-2-cyanopropionic acid (41234-20-2)

Guidance literature:

Cyanozimtsaeure (5), NaBH4;

DOI:10.1016/S0040-4020(01)99378-0

Reference yield: 81.4%

3-(2-bromo-4,5-dimethoxyphenyl)-2-cyanopropionic acid (41234-20-2) → 3-(2-bromo-4,5-dimethoxyphenyl)propanenitrile (35249-62-8)

Guidance literature:

In ISOPROPYLAMIDE; at 170 ℃; for 2h;

DOI:10.3184/030823409X4655259

upstream raw materials:

3-(2-bromo-4,5-dimethoxyphenyl)-2-cyanoacrylic acid

Downstream raw materials:

3-(2-bromo-4,5-dimethoxyphenyl)propanenitrile

Refernces