Technology Process of 20-(4-tert-butyldiphenylsiloxyphenyl)-1-eicosyne
There total 6 articles about 20-(4-tert-butyldiphenylsiloxyphenyl)-1-eicosyne which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
1H-imidazole; dmap;
In
N,N-dimethyl-formamide;
for 15h;
Ambient temperature;
DOI:10.1021/jo982260t
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 88 percent / (Ph3P)3Pd, CuI, i-Pr2NH / 15 h / Ambient temperature
2: 41 percent / Li, 1,3-diaminopropane, t-BuOK / 20 h / 65 °C
3: 97 percent / imidazole, DMAP / dimethylformamide / 15 h / Ambient temperature
With
1H-imidazole; dmap; copper(l) iodide; tris(triphenylphosphano)palladium; potassium tert-butylate; lithium; Trimethylenediamine; diisopropylamine;
In
N,N-dimethyl-formamide;
DOI:10.1021/jo982260t
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 99 percent / Br2 / diethyl ether / 0.5 h / 0 °C
2: 71 percent / LDA / tetrahydrofuran / 1.) 0 deg C, 3 h, 2.) room temperature, overnight
3: 88 percent / (Ph3P)3Pd, CuI, i-Pr2NH / 15 h / Ambient temperature
4: 41 percent / Li, 1,3-diaminopropane, t-BuOK / 20 h / 65 °C
5: 97 percent / imidazole, DMAP / dimethylformamide / 15 h / Ambient temperature
With
1H-imidazole; dmap; copper(l) iodide; tris(triphenylphosphano)palladium; potassium tert-butylate; bromine; lithium; Trimethylenediamine; diisopropylamine; lithium diisopropyl amide;
In
tetrahydrofuran; diethyl ether; N,N-dimethyl-formamide;
DOI:10.1021/jo982260t
