2-(4-bromophenyl)-8-(4-fluorobenzyl)-4-(4-flu orophenyl)-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine

Base Information

Chemical Name:2-(4-bromophenyl)-8-(4-fluorobenzyl)-4-(4-flu orophenyl)-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine
CAS No.:1360596-07-1
Molecular Formula:C₂₆H₁₉BrF₂N₂S
Molecular Weight:509.417
Hs Code.:

Synonyms:2-(4-bromophenyl)-8-(4-fluorobenzyl)-4-(4-flu orophenyl)-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-bromophenyl)-8-(4-fluorobenzyl)-4-(4-flu orophenyl)-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine

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Technology Process of 2-(4-bromophenyl)-8-(4-fluorobenzyl)-4-(4-flu orophenyl)-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine

There total 1 articles about 2-(4-bromophenyl)-8-(4-fluorobenzyl)-4-(4-flu orophenyl)-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 1072-72-6
Tetrahydrothiopyran-4-one

: 22265-36-7
4-bromobenzamidine

: 459-57-4
4-fluorobenzaldehyde

: 1360596-07-1
2-(4-bromophenyl)-8-(4-fluorobenzyl)-4-(4-flu orophenyl)-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidine

Guidance literature:: With potassium tert-butylate; In tert-butyl alcohol; at 140 ℃; for 0.283333h; regiospecific reaction; Microwave irradiation;
DOI:10.1016/j.tetlet.2011.12.128