methyl 3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propanoate

Base Information

Chemical Name:methyl 3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propanoate
CAS No.:1051372-05-4
Molecular Formula:C₁₂H₁₀ClFN₂O₃
Molecular Weight:284.674
Hs Code.:

Synonyms:methyl 3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl 3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propanoate

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Technology Process of methyl 3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propanoate

There total 1 articles about methyl 3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1051372-42-9
3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propionic acid

: 18107-18-1
diazomethyl-trimethyl-silane

: 1051372-05-4
methyl 3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propanoate

Guidance literature:: In methanol; hexane; toluene; at 20 ℃;
DOI:10.1021/jm800463f

Reference yield: 84.0%

: 1051372-05-4
methyl 3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propanoate

: 1051372-06-5
3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propan-1-ol

Guidance literature:: With diisobutylaluminium hydride; In dichloromethane; toluene; at 20 ℃; Inert atmosphere; Cooling with ice;
DOI:10.1021/jm800463f

Reference yield:

: 1051372-05-4
methyl 3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propanoate

: 1051372-08-7
3-(3-(2-chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)propanal

Guidance literature:: With diisobutylaluminium hydride; In dichloromethane; toluene; at -78 ℃; for 1h; Inert atmosphere;
DOI:10.1021/jm800463f