(R)-tert-butyl 4-(3,4-dimethoxyphenethyl)-2,2-dimethyloxazolidine-3-carboxylate

Base Information

Chemical Name:(R)-tert-butyl 4-(3,4-dimethoxyphenethyl)-2,2-dimethyloxazolidine-3-carboxylate
CAS No.:1428650-46-7
Molecular Formula:C₂₀H₃₁NO₅
Molecular Weight:365.47
Hs Code.:

Synonyms:(R)-tert-butyl 4-(3,4-dimethoxyphenethyl)-2,2-dimethyloxazolidine-3-carboxylate

Suppliers and Price of (R)-tert-butyl 4-(3,4-dimethoxyphenethyl)-2,2-dimethyloxazolidine-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of (R)-tert-butyl 4-(3,4-dimethoxyphenethyl)-2,2-dimethyloxazolidine-3-carboxylate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-tert-butyl 4-(3,4-dimethoxyphenethyl)-2,2-dimethyloxazolidine-3-carboxylate

There total 6 articles about (R)-tert-butyl 4-(3,4-dimethoxyphenethyl)-2,2-dimethyloxazolidine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 1434253-87-8
C₂₃H₃₅NO₅S₂

: 1428650-46-7
(R)-tert-butyl 4-(3,4-dimethoxyphenethyl)-2,2-dimethyloxazolidine-3-carboxylate

Guidance literature:: With sodium tetrahydroborate; nickel(II) chloride hexahydrate; In tetrahydrofuran; methanol; at 0 - 30 ℃;
DOI:10.1002/ejoc.201201128

Reference yield:

: C₂₀H₂₉NO₅

: 1428650-46-7
(R)-tert-butyl 4-(3,4-dimethoxyphenethyl)-2,2-dimethyloxazolidine-3-carboxylate

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 20 ℃; for 1h; under 760.051 Torr;
DOI:10.1016/j.tetasy.2013.02.003

Reference yield:

: 50766-67-1
2-(3,4-dimethoxyphenyl)-1,3-dithiane

: 1428650-46-7
(R)-tert-butyl 4-(3,4-dimethoxyphenethyl)-2,2-dimethyloxazolidine-3-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.67 h / -20 °C

1.2: -20 °C

2.1: nickel(II) chloride hexahydrate; sodium tetrahydroborate / tetrahydrofuran; methanol / 0 - 30 °C

With sodium tetrahydroborate; n-butyllithium; nickel(II) chloride hexahydrate; In tetrahydrofuran; methanol; hexane;
DOI:10.1002/ejoc.201201128