(R)-2-((tert-butoxycarbonyl)amino)-2-phenylpropanoic acid

Base Information

Chemical Name:(R)-2-((tert-butoxycarbonyl)amino)-2-phenylpropanoic acid
CAS No.:365442-14-4
Molecular Formula:C₁₄H₁₉NO₄
Molecular Weight:265.309
Hs Code.:

Synonyms:(R)-2-((tert-butoxycarbonyl)amino)-2-phenylpropanoic acid

Suppliers and Price of (R)-2-((tert-butoxycarbonyl)amino)-2-phenylpropanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(R)-2-((tert-Butoxycarbonyl)amino)-2-phenylpropanoicacid 97%
250mg
$ 315.00

Crysdot
(R)-2-((tert-Butoxycarbonyl)amino)-2-phenylpropanoicacid 97%
1g
$ 787.00

Alichem
(R)-2-((tert-Butoxycarbonyl)amino)-2-phenylpropanoicacid
5g
$ 1689.73

Alichem
(R)-2-((tert-Butoxycarbonyl)amino)-2-phenylpropanoicacid
1g
$ 811.89

Alichem
(R)-2-((tert-Butoxycarbonyl)amino)-2-phenylpropanoicacid
250mg
$ 361.80

Total 7 raw suppliers

Chemical Property of (R)-2-((tert-butoxycarbonyl)amino)-2-phenylpropanoic acid

Chemical Property:

Purity/Quality:

99%, ^*data from raw suppliers

(R)-2-((tert-Butoxycarbonyl)amino)-2-phenylpropanoicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-2-((tert-butoxycarbonyl)amino)-2-phenylpropanoic acid

There total 11 articles about (R)-2-((tert-butoxycarbonyl)amino)-2-phenylpropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1421045-74-0
tert-butyl ((S,E)-4-((2R,5R,6R)-5,6-dimethoxy-5,6-dimethyl-1,4-dioxan-2-yl)-2-phenylbut-3-en-2-yl)carbamate

: 365442-14-4
(R)-2-((tert-butoxycarbonyl)amino)-2-phenylpropanoic acid

Guidance literature:: With sodium periodate; ruthenium(III) trichloride hydrate; In tetrachloromethane; water; acetonitrile; at 20 ℃; Inert atmosphere;
DOI:10.1002/asia.201200859

Reference yield:

: 365442-07-5
(2R,3R)-3-tert-butoxycarbonylamino-3-phenylbutan-1,2-diol

: 365442-14-4
(R)-2-((tert-butoxycarbonyl)amino)-2-phenylpropanoic acid

Guidance literature:: With potassium permanganate; sodium periodate; sodium carbonate; In 1,4-dioxane; water; at 20 ℃;
DOI:10.1016/S0040-4020(01)00503-8

Reference yield:

: 945-93-7,13979-22-1,1504-72-9
ethyl (E)-3-phenylbut-2-enoate

: 365442-14-4
(R)-2-((tert-butoxycarbonyl)amino)-2-phenylpropanoic acid

Guidance literature:: Multi-step reaction with 5 steps

1: 93 percent / DIBALH / diethyl ether; hexane / 0 - 20 °C

2: t-BuOOH; L-(+)-diethyl tartrate; titanium tetraisopropoxide / 4 Angstroem molecular sieves / CH₂Cl₂; 2,2,4-trimethyl-pentane / 4 h / -20 °C

3: LiClO₄; NaN₃ / acetonitrile / 24 h / 65 °C

4: H₂ / Pd/C / ethyl acetate / 5 h / 20 °C

5: Na₂CO₃; NaIO₄; KMnO₄ / dioxane; H₂O / 20 °C

With titanium(IV) isopropylate; tert.-butylhydroperoxide; potassium permanganate; sodium periodate; sodium azide; diethyl (2R,3R)-tartrate; hydrogen; lithium perchlorate; diisobutylaluminium hydride; sodium carbonate; palladium on activated charcoal; 4 A molecular sieve; In 1,4-dioxane; 2,2,4-trimethylpentane; diethyl ether; hexane; dichloromethane; water; ethyl acetate; acetonitrile;
DOI:10.1016/S0040-4020(01)00503-8