N-ethyl-N-(3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl)-6-quinolinesulfonamide hydrochloride

Base Information

Chemical Name:N-ethyl-N-(3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl)-6-quinolinesulfonamide hydrochloride
CAS No.:1350978-18-5
Molecular Formula:C₂₅H₃₂N₄O₃S*ClH
Molecular Weight:505.081
Hs Code.:

Synonyms:N-ethyl-N-(3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl)-6-quinolinesulfonamide hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-ethyl-N-(3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl)-6-quinolinesulfonamide hydrochloride

Chemical Property:

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Technology Process of N-ethyl-N-(3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl)-6-quinolinesulfonamide hydrochloride

There total 4 articles about N-ethyl-N-(3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl)-6-quinolinesulfonamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1351184-60-5
N-ethyl-N-(3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl)-6-quinolinesulfonamide

: 1350978-18-5
N-ethyl-N-(3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl)-6-quinolinesulfonamide hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 20 ℃;
DOI:10.1016/j.bmc.2011.09.044

Reference yield:

: 793672-13-6
N-ethyl-N-(3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl)amine

: 1350978-18-5
N-ethyl-N-(3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl)-6-quinolinesulfonamide hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 20 °C

2: hydrogenchloride / 1,4-dioxane / 20 °C

With hydrogenchloride; triethylamine; In 1,4-dioxane; dichloromethane;
DOI:10.1016/j.bmc.2011.09.044

Reference yield:

: 263017-65-8
N-{3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl}acetamide

: 1350978-18-5
N-ethyl-N-(3-[4-(2-methoxyphenyl)piperazin-1-yl]propyl)-6-quinolinesulfonamide hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / Inert atmosphere; Reflux

2: triethylamine / dichloromethane / 20 °C

3: hydrogenchloride / 1,4-dioxane / 20 °C

With hydrogenchloride; lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; 1,4-dioxane; dichloromethane;
DOI:10.1016/j.bmc.2011.09.044