N-(2-hydroxy-4-methoxybenzyl)alanine

Base Information

Chemical Name:N-(2-hydroxy-4-methoxybenzyl)alanine
CAS No.:148515-73-5
Molecular Formula:C₁₁H₁₅NO₄
Molecular Weight:225.244
Hs Code.:
DSSTox Substance ID:DTXSID201245067
Nikkaji Number:J824.826E

Synonyms:SCHEMBL3050118;DTXSID201245067;N-(2-hydroxy-4-methoxybenzyl)alanine;N-(2-Hydroxy-4-methoxybenzyl)-L-alanine;N-[(2-Hydroxy-4-methoxyphenyl)methyl]-L-alanine;148515-73-5

Suppliers and Price of N-(2-hydroxy-4-methoxybenzyl)alanine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(2-hydroxy-4-methoxybenzyl)alanine

Chemical Property:

XLogP3:-0.8
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:225.10010796
Heavy Atom Count:16
Complexity:234

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C(=O)O)NCC1=C(C=C(C=C1)OC)O
Isomeric SMILES:C[C@@H](C(=O)O)NCC1=C(C=C(C=C1)OC)O

Technology Process of N-(2-hydroxy-4-methoxybenzyl)alanine

There total 3 articles about N-(2-hydroxy-4-methoxybenzyl)alanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (S)-2-{[1-(2-Hydroxy-4-methoxy-phenyl)-meth-(E)-ylidene]-amino}-propionic acid

: 148515-73-5
(S)-2-(2-Hydroxy-4-methoxy-benzylamino)-propionic acid

Guidance literature:: With sodium tetrahydroborate; In methanol; for 0.5h; Yield given; Ambient temperature;

Reference yield:

: 673-22-3
2-Hydroxy-4-methoxybenzaldehyde

: 148515-73-5
(S)-2-(2-Hydroxy-4-methoxy-benzylamino)-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: H₂O / 2 h / Ambient temperature; pH=9-9.5

2: NaBH₄ / H₂O / 1 h / 5 - 10 °C

With sodium tetrahydroborate; In water;
DOI:10.1016/S0040-4039(97)00303-1

Reference yield:

: 673-22-3
2-Hydroxy-4-methoxybenzaldehyde

: 148515-73-5
(S)-2-(2-Hydroxy-4-methoxy-benzylamino)-propionic acid

Guidance literature:: Multi-step reaction with 2 steps

1: KOH / methanol / 0.5 h / Ambient temperature

2: NaBH₄ / methanol / 0.5 h / Ambient temperature

With potassium hydroxide; sodium tetrahydroborate; In methanol;