1,8-bis(3-(ethoxymethoxy)-1,4,5,6,8-pentamethoxynaphthalen-2-yl)octa-3,5-diyne-2,7-diol

Base Information

• Chemical Name: 1,8-bis(3-(ethoxymethoxy)-1,4,5,6,8-pentamethoxynaphthalen-2-yl)octa-3,5-diyne-2,7-diol
• CAS No.: 1198596-77-8
• Molecular Formula: C₄₄H₅₄O₁₆
• Molecular Weight: 838.903
• Mol file: 1198596-77-8.mol

Synonyms:1,8-bis(3-(ethoxymethoxy)-1,4,5,6,8-pentamethoxynaphthalen-2-yl)octa-3,5-diyne-2,7-diol

Chemical Property of 1,8-bis(3-(ethoxymethoxy)-1,4,5,6,8-pentamethoxynaphthalen-2-yl)octa-3,5-diyne-2,7-diol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,8-bis(3-(ethoxymethoxy)-1,4,5,6,8-pentamethoxynaphthalen-2-yl)octa-3,5-diyne-2,7-diol

There total 2 articles about 1,8-bis(3-(ethoxymethoxy)-1,4,5,6,8-pentamethoxynaphthalen-2-yl)octa-3,5-diyne-2,7-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

C22H28O8 (1198596-76-7) + 7-(benzyloxy)-6-bromo-8-methoxy-3-methyl-1H-isochromen-1-one → 1,8-bis(3-(ethoxymethoxy)-1,4,5,6,8-pentamethoxynaphthalen-2-yl)octa-3,5-diyne-2,7-diol (1198596-77-8) + 7-(benzyloxy)-6-(4-(3-(ethoxymethoxy)-1,4,5,6,8-pentamethoxynaphthalen-2-yl)-3-hydroxybut-1-yn-1-yl)-8-methoxy-3-methyl-1H-isochromen-1-one

Guidance literature:

With copper(l) iodide; palladium diacetate; triethylamine; triphenylphosphine; In N,N-dimethyl-formamide; at 20 ℃; for 25h; Inert atmosphere;

DOI:10.1016/j.tet.2014.11.030

Reference yield:

C15H19IO7 (1198596-74-5) + C22H28O8 (1198596-76-7) → methyl 3-(ethoxymethoxy)-4-(4-(3-(ethoxymethoxy)-1,4,5,6,8-pentamethoxynaphthalen-2-yl)-3-hydroxybut-1-ynyl)-2-methoxy-6-(2-methoxy-2-oxoethyl)benzoate (1198596-61-0) + 1,8-bis(3-(ethoxymethoxy)-1,4,5,6,8-pentamethoxynaphthalen-2-yl)octa-3,5-diyne-2,7-diol (1198596-77-8)

Guidance literature:

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 16.5h; Inert atmosphere;

DOI:10.1002/anie.200903316

upstream raw materials:

C₁₅H₁₉IO₇

C₂₂H₂₈O₈