4-Fluoroindoline

Base Information

Chemical Name:4-Fluoroindoline
CAS No.:552866-98-5
Molecular Formula:C8H8FN
Molecular Weight:137.157
Hs Code.:2933990090
DSSTox Substance ID:DTXSID50585690
Wikidata:Q72479670
Mol file:552866-98-5.mol

Synonyms:4-Fluoroindoline;552866-98-5;4-FLUORO-2,3-DIHYDRO-1H-INDOLE;4-Fluoro-2,3-dihydro-indole;MFCD07371634;1H-Indole, 4-fluoro-2,3-dihydro-;1H-INDOLE,4-FLUORO-2,3-DIHYDRO;4-fluoro-indoline;SCHEMBL550313;3-Nitro-4-chlorobenzoylchloride;DTXSID50585690;CMQOXZRRFDMQKY-UHFFFAOYSA-N;4-fluoro-2,3-dihydro-1 H-indole;1H-Indole,4-fluoro-2,3-dihydro-;AKOS006239294;SB37638;BS-28619;SY129312;AM20040706;CS-0060380;4-Fluoro-2,3-dihydro-1H-indole, AldrichCPR;EN300-151555;A830573;J-515407

Suppliers and Price of 4-Fluoroindoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Fluoro-2,3-dihydro-1H-indole
250mg
$ 75.00

Matrix Scientific
4-Fluoroindoline
10g
$ 1722.00

Matrix Scientific
4-Fluoroindoline
5g
$ 1078.00

Matrix Scientific
4-Fluoroindoline
1g
$ 342.00

Labseeker
1H-INDOLE,4-FLUORO-2,3-DIHYDRO 95
1g
$ 523.00

J&W Pharmlab
4-Fluoro-2,3-dihydro-1H-indole 97%
5g
$ 490.00

J&W Pharmlab
4-Fluoro-2,3-dihydro-1H-indole 97%
1g
$ 145.00

J&W Pharmlab
4-Fluoro-2,3-dihydro-1H-indole 97%
500mg
$ 125.00

J&W Pharmlab
4-Fluoro-2,3-dihydro-1H-indole 97%
250mg
$ 110.00

J&W Pharmlab
4-Fluoro-2,3-dihydro-1H-indole 97%
100mg
$ 95.00

Total 32 raw suppliers

Chemical Property of 4-Fluoroindoline

Chemical Property:

Vapor Pressure:0.146mmHg at 25°C
Refractive Index:1.538
Boiling Point:215.7 °C at 760 mmHg
PKA:4.29±0.20(Predicted)
Flash Point:84.2 °C
PSA：12.03000
Density:1.154 g/cm³
LogP:1.93170
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:137.064077422
Heavy Atom Count:10
Complexity:126

Purity/Quality:

99%, ^*data from raw suppliers

4-Fluoro-2,3-dihydro-1H-indole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CNC2=C1C(=CC=C2)F

Technology Process of 4-Fluoroindoline

There total 3 articles about 4-Fluoroindoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 387-43-9
4-fluoroindole

: 552866-98-5
2,3-dihydro-4-fluoro-1H-indole

Guidance literature:: 4-fluoroindole; With sodium cyanoborohydride; acetic acid; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

With water; sodium hydroxide; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2014.01.028

Reference yield:

: 344790-94-9
1-(2-(2-fluoro-6-nitrophenyl)vinyl)pyrrolidine

: 552866-98-5
2,3-dihydro-4-fluoro-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogen / nickel / methanol / 20 h / 20 °C / 760.05 Torr

2: sodium cyanoborohydride; acetic acid / 0 - 20 °C

With hydrogen; sodium cyanoborohydride; acetic acid; nickel; In methanol;

Reference yield:

: 769-10-8
1-fluoro-2-methyl-3-nitrobenzene

: 552866-98-5
2,3-dihydro-4-fluoro-1H-indole

Guidance literature:: Multi-step reaction with 3 steps

1: 48 h / Reflux

2: hydrogen / nickel / methanol / 20 h / 20 °C / 760.05 Torr

3: sodium cyanoborohydride; acetic acid / 0 - 20 °C

With hydrogen; sodium cyanoborohydride; acetic acid; nickel; In methanol;