4-(tert-butyl)-2-chloronitrobenzene

Base Information

• Chemical Name: 4-(tert-butyl)-2-chloronitrobenzene
• CAS No.: 90869-73-1
• Molecular Formula: C₁₀H₁₂ClNO₂
• Molecular Weight: 213.664
• Mol file: 90869-73-1.mol

Synonyms:4-(tert-butyl)-2-chloronitrobenzene

Chemical Property of 4-(tert-butyl)-2-chloronitrobenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(tert-butyl)-2-chloronitrobenzene

There total 3 articles about 4-(tert-butyl)-2-chloronitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-(tert-butyl)-2-nitroaniline (142564-53-2) → 4-(tert-butyl)-2-chloronitrobenzene (90869-73-1)

Guidance literature:

5-(tert-butyl)-2-nitroaniline; With hydrogenchloride; sodium nitrite; In water; at 20 ℃; for 1h;

With hydrogenchloride; copper(l) chloride; In water; at 100 ℃; for 1h;

DOI:10.1021/acs.joc.7b02025

Reference yield:

acetic acid-(5-tert-butyl-2-nitro-anilide) (6933-55-7) → 4-(tert-butyl)-2-chloronitrobenzene (90869-73-1)

Guidance literature:

With hydrogenchloride; Behandeln des Reaktionsgemisches mit wss. Natriumnitrit-Loesung bei 5grad und Eintragen der erhaltenen Loesung in eine Loesung von Kupfer(I)-chlorid in konz. wss. Salzsaeure bei 60grad;

DOI:10.1039/jr9570000600

Reference yield:

3-tert-butylaniline (5369-19-7) → 4-(tert-butyl)-2-chloronitrobenzene (90869-73-1)

Guidance literature:

Multi-step reaction with 2 steps

1: Cu(NO₃)2

2: aqueous hydrochloric acid / Behandeln des Reaktionsgemisches mit wss. Natriumnitrit-Loesung bei 5grad und Eintragen der erhaltenen Loesung in eine Loesung von Kupfer(I)-chlorid in konz. wss. Salzsaeure bei 60grad

With hydrogenchloride; copper(II) nitrate;

DOI:10.1039/jr9570000600

upstream raw materials:

acetic acid-(5-tert-butyl-2-nitro-anilide)

3-tert-butylaniline

5-(tert-butyl)-2-nitroaniline

Refernces