Technology Process of (3aS*,7aS*)-1-benzyl-3a,4,5,6,7,7a-hexahydro-3a-(3',4'-methylenedioxyphenyl)-6-oxoindoline
There total 7 articles about (3aS*,7aS*)-1-benzyl-3a,4,5,6,7,7a-hexahydro-3a-(3',4'-methylenedioxyphenyl)-6-oxoindoline which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
benzylamine hydrochloride; sodium sulfate;
In
acetonitrile;
for 5h;
Heating / reflux;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 256 mg
2: 87.4 percent / osmium tetroxide (OsO4), sodium metaperiodate (NaIO4) / dioxane; H2O
3: 1.) K2CO3, NaBH4; 2.) HCl (10percent) / 1.) MeOH, room temp., 3 h; 2.) reflux, 0.5 h
With
hydrogenchloride; sodium tetrahydroborate; sodium periodate; osmium(VIII) oxide; potassium carbonate;
In
1,4-dioxane; water;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 79 percent / sodium borohydride (NaBH4) / methanol / 2 h / Ambient temperature
2: 256 mg
3: 87.4 percent / osmium tetroxide (OsO4), sodium metaperiodate (NaIO4) / dioxane; H2O
4: 1.) K2CO3, NaBH4; 2.) HCl (10percent) / 1.) MeOH, room temp., 3 h; 2.) reflux, 0.5 h
With
hydrogenchloride; sodium tetrahydroborate; sodium periodate; osmium(VIII) oxide; potassium carbonate;
In
1,4-dioxane; methanol; water;
