2-¹³C-3-[(N-methyl-N-(4-methylphenyl)amino)]propanoyl hydrazide

Base Information

• Chemical Name: 2-¹³C-3-[(N-methyl-N-(4-methylphenyl)amino)]propanoyl hydrazide
• CAS No.: 1400771-08-5
• Molecular Formula: C₁₁H₁₇N₃O
• Molecular Weight: 208.264
• Mol file: 1400771-08-5.mol

Synonyms:2-¹³C-3-[(N-methyl-N-(4-methylphenyl)amino)]propanoyl hydrazide

Chemical Property of 2-¹³C-3-[(N-methyl-N-(4-methylphenyl)amino)]propanoyl hydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-¹³C-3-[(N-methyl-N-(4-methylphenyl)amino)]propanoyl hydrazide

There total 2 articles about 2-¹³C-3-[(N-methyl-N-(4-methylphenyl)amino)]propanoyl hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

methyl 2-13C-3-(N-methyl-N-(4-methylphenyl)amino)propanoate → 2-13C-3-[(N-methyl-N-(4-methylphenyl)amino)]propanoyl hydrazide (1400771-08-5)

Guidance literature:

With hydrazine hydrate; In ethanol; at 20 ℃; for 2h;

DOI:10.1021/ml300132t

Reference yield:

N-methyl-p-toluidine (623-08-5) → 2-13C-3-[(N-methyl-N-(4-methylphenyl)amino)]propanoyl hydrazide (1400771-08-5)

Guidance literature:

Multi-step reaction with 2 steps

1: copper(l) chloride; acetic acid / 120 °C

2: hydrazine hydrate / ethanol / 2 h / 20 °C

With hydrazine hydrate; acetic acid; copper(l) chloride; In ethanol;

DOI:10.1021/ml300132t

Reference yield:

2-13C-3-[(N-methyl-N-(4-methylphenyl)amino)]propanoyl hydrazide (1400771-08-5) → C9(13)CH14NO4P(2-) + C9(13)CH14NO4P(2-) + C9(13)CH14(2)HNO (1400771-15-4) + C9(13)CH14(2)HNO (1400771-16-5)

Guidance literature:

Multi-step reaction with 4 steps

1: acetic acid; sodium nitrite / dichloromethane; water

2: dichloromethane / 20 °C / Inert atmosphere

3: dimethyl sulfoxide / 48 h / 20 °C / Inert atmosphere; Darkness

4: water-d2 / dimethylsulfoxide-d6 / 0.17 h / 37 °C

With water-d2; acetic acid; sodium nitrite; In dimethylsulfoxide-d6; dichloromethane; water; dimethyl sulfoxide;

DOI:10.1021/ml300132t

upstream raw materials:

N-methyl-p-toluidine

Downstream raw materials:

C₉⁽¹³⁾CH₁₄⁽²⁾HNO

C₉⁽¹³⁾CH₁₄⁽²⁾HNO