6-chloro-1-(2-nitrophenyl)spiro

Base Information

Chemical Name:6-chloro-1-(2-nitrophenyl)spiro
CAS No.:75391-90-1
Molecular Formula:C₁₈H₁₈ClN₃O₂
Molecular Weight:343.813
Hs Code.:

6-chloro-1-(2-nitrophenyl)spiro<indoline-3,4'-piperidine>

Synonyms:6-chloro-1-(2-nitrophenyl)spiro

Suppliers and Price of 6-chloro-1-(2-nitrophenyl)spiro

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 6-chloro-1-(2-nitrophenyl)spiro

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 6-chloro-1-(2-nitrophenyl)spiro

There total 4 articles about 6-chloro-1-(2-nitrophenyl)spiro which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 75391-89-8
6-chloro-1-(2-nitrophenyl)-1'-(phenoxycarbonyl)spiro

: 75391-90-1
6-chloro-1-(2-nitrophenyl)spiro

Guidance literature:: With potassium hydroxide; In ethylene glycol; at 160 - 170 ℃; for 2h;
DOI:10.1021/jm00361a009

Reference yield:

: 75391-76-3
4-chloro-1'-methylspiro

: 75391-90-1
6-chloro-1-(2-nitrophenyl)spiro

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / 5 h / 170 - 175 °C

2: 85 percent / K₂CO₃ / CH₂Cl₂ / 2 h / Ambient temperature

3: 3 N HCl / 16 h / Heating

With hydrogenchloride; potassium carbonate; In dichloromethane;
DOI:10.1021/jm00361a009

Reference yield:

: 75391-75-2
4-(4-chloro-2-fluorophenyl)-4-cyano-1-methylpiperidine

: 75391-90-1
6-chloro-1-(2-nitrophenyl)spiro

Guidance literature:: Multi-step reaction with 4 steps

1: 93 percent / lithium triethoxyaluminum hydride, lithium aluminum hydride / 1,2-dimethoxy-ethane / 72 h / Heating

2: 84 percent / 5 h / 170 - 175 °C

3: 85 percent / K₂CO₃ / CH₂Cl₂ / 2 h / Ambient temperature

4: 3 N HCl / 16 h / Heating

With hydrogenchloride; lithium aluminium tetrahydride; potassium carbonate; lithium triethoxyaluminum hydride; In 1,2-dimethoxyethane; dichloromethane;
DOI:10.1021/jm00361a009