Ethyl [6-({3,3-dimethyl-5-[4-(trifluoromethyl)phenyl]-2,3-dihydro-1H-indol-1-yl}sulphonyl)-2,3-dihydro-1H-inden-1-yl]acetate

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Chemical Name:Ethyl [6-({3,3-dimethyl-5-[4-(trifluoromethyl)phenyl]-2,3-dihydro-1H-indol-1-yl}sulphonyl)-2,3-dihydro-1H-inden-1-yl]acetate
CAS No.:844901-60-6
Molecular Formula:C₃₀H₃₀F₃NO₄S
Molecular Weight:557.634
Hs Code.:

Synonyms:Ethyl [6-({3,3-dimethyl-5-[4-(trifluoromethyl)phenyl]-2,3-dihydro-1H-indol-1-yl}sulphonyl)-2,3-dihydro-1H-inden-1-yl]acetate

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Chemical Property of Ethyl [6-({3,3-dimethyl-5-[4-(trifluoromethyl)phenyl]-2,3-dihydro-1H-indol-1-yl}sulphonyl)-2,3-dihydro-1H-inden-1-yl]acetate

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Technology Process of Ethyl [6-({3,3-dimethyl-5-[4-(trifluoromethyl)phenyl]-2,3-dihydro-1H-indol-1-yl}sulphonyl)-2,3-dihydro-1H-inden-1-yl]acetate

There total 1 articles about Ethyl [6-({3,3-dimethyl-5-[4-(trifluoromethyl)phenyl]-2,3-dihydro-1H-indol-1-yl}sulphonyl)-2,3-dihydro-1H-inden-1-yl]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 7791-25-5
sulfuryl dichloride

: 844901-59-3
Ethyl [6-(chlorosulphonyl)-2,3-dihydro-1H-inden-1-yl]acetate

: 844901-56-0
3,3-dimethyl-5-[4-(trifluoromethyl)phenyl]-2,3-dihydro-1H-indole

: 844901-60-6
Ethyl [6-({3,3-dimethyl-5-[4-(trifluoromethyl)phenyl]-2,3-dihydro-1H-indol-1-yl}sulphonyl)-2,3-dihydro-1H-inden-1-yl]acetate

Guidance literature:: With dmap; triethylamine; In dichloromethane; water; ethyl acetate;

Reference yield: 91.0%

: 844901-60-6
Ethyl [6-({3,3-dimethyl-5-[4-(trifluoromethyl)phenyl]-2,3-dihydro-1H-indol-1-yl}sulphonyl)-2,3-dihydro-1H-inden-1-yl]acetate

: [6-({3,3-Dimethyl-5-[4-(trifluoromethyl)phenyl]-2,3-dihydro-1H-indol-1-yl}sulphonyl)-2,3-dihydro-1H-inden-1-yl]acetic acid

Guidance literature:: Ethyl [6-({3,3-dimethyl-5-[4-(trifluoromethyl)phenyl]-2,3-dihydro-1H-indol-1-yl}sulphonyl)-2,3-dihydro-1H-inden-1-yl]acetate; With lithium hydroxide; water; In tetrahydrofuran; methanol; at 50 ℃; for 1h;

With hydrogenchloride; In tetrahydrofuran; methanol; water;