p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-p-tolyl-4-pyrimidinyl]benzenesulfonamide

Base Information

Chemical Name:p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-p-tolyl-4-pyrimidinyl]benzenesulfonamide
CAS No.:146532-04-9
Molecular Formula:C₂₃H₂₇N₃O₄S
Molecular Weight:441.551
Hs Code.:

Synonyms:p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-p-tolyl-4-pyrimidinyl]benzenesulfonamide

Suppliers and Price of p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-p-tolyl-4-pyrimidinyl]benzenesulfonamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-p-tolyl-4-pyrimidinyl]benzenesulfonamide

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Technology Process of p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-p-tolyl-4-pyrimidinyl]benzenesulfonamide

There total 1 articles about p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-p-tolyl-4-pyrimidinyl]benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 146533-13-3
4-tert-butyl-N-[6-chloro-5-(p-tolyl)-4-pyrimidinyl]-benzene sulfonamide

: 146532-04-9
p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-p-tolyl-4-pyrimidinyl]benzenesulfonamide

Guidance literature:: In ethylene glycol;

Reference yield: 88.0%

: 32779-36-5
5-Bromo-2-chloropyrimidine

: 146532-04-9
p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-p-tolyl-4-pyrimidinyl]benzenesulfonamide

: 169677-30-9
N-[6-{2-(5-Bromopyrimidin-2-yloxy)ethoxy}-5-(4-methylphenyl)-pyrimidin-4-yl]-4-tert-butylbenzenesulfonamide

Guidance literature:: p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-p-tolyl-4-pyrimidinyl]benzenesulfonamide; With sodium hydride; In N,N-dimethyl acetamide; at 0 ℃; for 0.333333h;

5-Bromo-2-chloropyrimidine; In N,N-dimethyl acetamide; at 20 ℃; for 7h; Further stages.;
DOI:10.1021/jm0102304

Reference yield: 19.0%

: 374068-01-6
2-bromopyrimidine-5-carboxylic acid

: 146532-04-9
p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-p-tolyl-4-pyrimidinyl]benzenesulfonamide

: 2-{2-[6-(4-tert-butyl-benzenesulfonylamino)-5-p-tolyl-pyrimidin-4-yloxy]-ethoxy}-pyrimidine-5-carboxylic acid

Guidance literature:: p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-p-tolyl-4-pyrimidinyl]benzenesulfonamide; With sodium hydride; In tetrahydrofuran; N,N-dimethyl acetamide; for 0.166667h;

2-bromopyrimidine-5-carboxylic acid; In tetrahydrofuran; N,N-dimethyl acetamide; at 20 ℃; for 2h; Further stages.;
DOI:10.1021/jm000538f