(R)-2-Amino-3-(benzyloxy)propan-1-ol

Base Information

Chemical Name:(R)-2-Amino-3-(benzyloxy)propan-1-ol
CAS No.:58577-87-0
Molecular Formula:C10H15 N O2
Molecular Weight:181.235
Hs Code.:2922509090
European Community (EC) Number:625-576-6
DSSTox Substance ID:DTXSID40974135
Nikkaji Number:J1.360.383I
Wikidata:Q76423595
Mol file:58577-87-0.mol

Synonyms:58577-87-0;(R)-2-Amino-3-(benzyloxy)propan-1-ol;(R)-(+)-2-Amino-3-benzyloxy-1-propanol;H-Serinol(Bzl);(R)-2-AMINO-3-BENZYLOXY-1-PROPANOL;(2R)-2-amino-3-(benzyloxy)propan-1-ol;(2R)-2-amino-3-phenylmethoxypropan-1-ol;O-benzyl-L-serinol;1-Propanol, 2-amino-3-(phenylmethoxy)-, (2R)-;MFCD00235943;serinol benzyl ether;H-Ser(Bzl)-ol;SCHEMBL82083;DTXSID40974135;ZJUOMDNENVWMPL-SNVBAGLBSA-N;AMY22003;(R)-2-amino-3-benzyloxypropan-1-ol;AKOS016843243;(R)-2-Amino-3-(phenylmethoxy)propanol;AS-33259;EN300-50179;(R)-(+)-2-Amino-3-benzyloxy-1-propanol, 97%;SEM

Suppliers and Price of (R)-2-Amino-3-(benzyloxy)propan-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(R)-(+)-2-Amino-3-benzyloxy-1-propanol
1g
$ 95.00

SynQuest Laboratories
(2R)-(+)-2-Amino-3-(benzyloxy)propan-1-ol
5 g
$ 472.00

Sigma-Aldrich
(R)-(+)-2-Amino-3-benzyloxy-1-propanol 97%
1g
$ 108.00

Medical Isotopes, Inc.
(R)-(+)-2-Amino-3-benzyloxy-1-propanol
25 g
$ 2760.00

Medical Isotopes, Inc.
(R)-(+)-2-Amino-3-benzyloxy-1-propanol
1 g
$ 610.00

Crysdot
H-Serinol(Bzl) 98%
25g
$ 465.00

Chem-Impex
O-Benzyl-L-serinolhydrochloride,98%(HPLC) 98%(HPLC)
5G
$ 168.00

Chem-Impex
O-Benzyl-L-serinolhydrochloride,≥98%(HPLC) ≥98%(HPLC)
25G
$ 547.46

Chem-Impex
O-Benzyl-L-serinolhydrochloride,98%(HPLC) 98%(HPLC)
1G
$ 44.80

Chem-Impex
O-Benzyl-L-serinolhydrochloride,≥98%(HPLC) ≥98%(HPLC)
250MG
$ 36.22

Total 53 raw suppliers

Chemical Property of (R)-2-Amino-3-(benzyloxy)propan-1-ol

Chemical Property:

Vapor Pressure:3.44E-05mmHg at 25°C
Melting Point:34-37 °C(lit.)
Refractive Index:1.5464 (estimate)
Boiling Point:307 °C(lit.)
PKA:12.53±0.10(Predicted)
Flash Point:159.4°C
PSA：55.48000
Density:1.11g/cm³
LogP:1.22310
Storage Temp.:Store at 0-5°C
Sensitive.:Air Sensitive
Solubility.:Chloroform (Slightly), Dichloromethane (Slightly), Methanol (Slightly)
XLogP3:0
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:181.110278721
Heavy Atom Count:13
Complexity:124

Purity/Quality:

97% ^*data from raw suppliers

(R)-(+)-2-Amino-3-benzyloxy-1-propanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:C
Statements: 34
Safety Statements: 26-27-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COCC(CO)N
Isomeric SMILES:C1=CC=C(C=C1)COC[C@@H](CO)N
Uses (R)-(+)-2-Amino-3-benzyloxy-1-propanol is used as a reagent to synthesize beta-amino alcohols, compounds that are used as therapeutic agents to treat heart disease. (R)-(+)-2-Amino-3-benzyloxy-1-propanol is also used as a reagent to synthesize 15-membered macrolide antibiotics, drugs that are used to treat respiratory tract infections.

Technology Process of (R)-2-Amino-3-(benzyloxy)propan-1-ol

There total 11 articles about (R)-2-Amino-3-(benzyloxy)propan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 58577-87-0
O-benzyl-L-serinol

Guidance literature:

Reference yield: 90.0%

: 4726-96-9,32520-12-0
O-Benzyl-L-serine

: 58577-87-0
O-benzyl-L-serinol

Guidance literature:: With lithium aluminium tetrahydride;

Reference yield: 61.0%

: (3S,6S)-3,6-bis((benzyloxy)methyl)piperazine-2,5-dione

: 58577-87-0
O-benzyl-L-serinol

Guidance literature:: With C₂₄H₂₀ClN₂OPRu; potassium tert-butylate; hydrogen; In tetrahydrofuran; at 110 ℃; for 48h; under 2280.15 - 30402 Torr; Inert atmosphere; Schlenk technique; Autoclave;
DOI:10.1039/d0cc04550k