(2R,4R)-4-(6-Benzoylamino-purin-9-yl)-pyrrolidine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester 2-pentafluorophenyl ester

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Chemical Name:(2R,4R)-4-(6-Benzoylamino-purin-9-yl)-pyrrolidine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester 2-pentafluorophenyl ester
CAS No.:457071-99-7
Molecular Formula:C₃₈H₂₅F₅N₆O₅
Molecular Weight:740.646
Hs Code.:

Synonyms:(2R,4R)-4-(6-Benzoylamino-purin-9-yl)-pyrrolidine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester 2-pentafluorophenyl ester

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Chemical Property of (2R,4R)-4-(6-Benzoylamino-purin-9-yl)-pyrrolidine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester 2-pentafluorophenyl ester

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Technology Process of (2R,4R)-4-(6-Benzoylamino-purin-9-yl)-pyrrolidine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester 2-pentafluorophenyl ester

There total 1 articles about (2R,4R)-4-(6-Benzoylamino-purin-9-yl)-pyrrolidine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester 2-pentafluorophenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 771-61-9
2,3,4,5,6-pentafluorophenol

: 82911-69-1
N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

: 189163-56-2
(2R,4R)-4-(6-Benzoylamino-purin-9-yl)-pyrrolidine-1,2-dicarboxylic acid 2-benzhydryl ester 1-tert-butyl ester

: 457071-99-7
(2R,4R)-4-(6-Benzoylamino-purin-9-yl)-pyrrolidine-1,2-dicarboxylic acid 1-(9H-fluoren-9-ylmethyl) ester 2-pentafluorophenyl ester

Guidance literature:: (2R,4R)-4-(6-Benzoylamino-purin-9-yl)-pyrrolidine-1,2-dicarboxylic acid 2-benzhydryl ester 1-tert-butyl ester; With trifluoroacetic acid; In methoxybenzene; at 30 ℃;

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide; With sodium hydrogencarbonate; In water; acetonitrile; at 30 ℃; pH=10;

2,3,4,5,6-pentafluorophenol; With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 30 ℃; for 1h;
DOI:10.1021/ol060448q