H-GAMMA-ABU-OTBU HCL

Base Information

• Chemical Name: H-GAMMA-ABU-OTBU HCL
• CAS No.: 58640-01-0
• Molecular Formula: C8H17 N O2 . Cl H
• Molecular Weight: 195.69
• Hs Code.: 2922499990
• Mol file: 58640-01-0.mol

Synonyms:Butanoicacid, 4-amino-, 1,1-dimethylethyl ester, hydrochloride (9CI); 4-Aminobutanoicacid tert-butyl ester hydrochloride; tert-Butyl 4-aminobutanoate hydrochloride;tert-Butyl g-aminobutyrate hydrochloride

Chemical Property of H-GAMMA-ABU-OTBU HCL

Chemical Property:

• PSA: 52.32000
• LogP: 2.56930
• Storage Temp.: 2-8°C
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl4-AminobutanoateHydrochloride ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Employed as an important intermediate for raw material for pharmaceutical.

Refernces

Synthesis, antifungal and nematocidal activities of thioureines with an aminoester sequence

10.1016/0223-5234(96)88299-7

This research presents the synthesis, antifungal, and anthelmintic activities of twenty-three arylthioureines, which were designed with p-alanine or γ-aminobutyric alkyl ester chains. The purpose of the study was to evaluate the in vitro efficacy of these compounds against 44 strains of fungi and two genera of nematodes. The findings indicated that nitro derivatives were particularly potent against Aspergillus and Candida strains, while ester chains enhanced activity against the filarial worm Molinema dessetae. Twelve compounds showed an EC50 of less than 40 μg/ml, yet their anthelmintic potency was found to be weaker compared to tetramisole. The chemicals used in the synthesis process included aromatic amines, isothiocyanates, and aminoesters of p-alanine or GABA, with the final thioureine compounds being characterized by various substituents on the phenyl ring and different alkyl ester groups.