(Z)-5-dimethylphenylsilyl-8-p-methoxybenzyloxy-1-(2-tetrahydropyranyloxy)-4-octene

Base Information

Chemical Name:(Z)-5-dimethylphenylsilyl-8-p-methoxybenzyloxy-1-(2-tetrahydropyranyloxy)-4-octene
CAS No.:460752-67-4
Molecular Formula:C₂₉H₄₂O₄Si
Molecular Weight:482.736
Hs Code.:

Synonyms:(Z)-5-dimethylphenylsilyl-8-p-methoxybenzyloxy-1-(2-tetrahydropyranyloxy)-4-octene

Suppliers and Price of (Z)-5-dimethylphenylsilyl-8-p-methoxybenzyloxy-1-(2-tetrahydropyranyloxy)-4-octene

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (Z)-5-dimethylphenylsilyl-8-p-methoxybenzyloxy-1-(2-tetrahydropyranyloxy)-4-octene

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Technology Process of (Z)-5-dimethylphenylsilyl-8-p-methoxybenzyloxy-1-(2-tetrahydropyranyloxy)-4-octene

There total 6 articles about (Z)-5-dimethylphenylsilyl-8-p-methoxybenzyloxy-1-(2-tetrahydropyranyloxy)-4-octene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 110-87-2
3,4-dihydro-2H-pyran

: 460752-67-4
(Z)-5-dimethylphenylsilyl-8-p-methoxybenzyloxy-1-(2-tetrahydropyranyloxy)-4-octene

Guidance literature:: Multi-step reaction with 4 steps

1.1: TsOH*H₂O / CH₂Cl₂

2.1: BuLi / tetrahydrofuran; hexane / -78 °C

2.2: tetrahydrofuran; hexane / -78 - 20 °C

3.1: DIBALH / diethyl ether; hexane / 30 h / 20 °C

3.2: 81 percent / pyridine; bromine / diethyl ether; hexane; CH₂Cl₂ / 0.5 h / -78 °C

4.1: BuLi / tetrahydrofuran; hexane / -78 °C

4.2: tetrahydrofuran; hexane / -78 °C

With n-butyllithium; diisobutylaluminium hydride; toluene-4-sulfonic acid; In tetrahydrofuran; diethyl ether; hexane; dichloromethane;
DOI:10.1021/jo026006j

Reference yield:

: 5390-04-5
pent-1-yn-5-ol

: 460752-67-4
(Z)-5-dimethylphenylsilyl-8-p-methoxybenzyloxy-1-(2-tetrahydropyranyloxy)-4-octene

Guidance literature:: Multi-step reaction with 4 steps

1.1: TsOH*H₂O / CH₂Cl₂

2.1: BuLi / tetrahydrofuran; hexane / -78 °C

2.2: tetrahydrofuran; hexane / -78 - 20 °C

3.1: DIBALH / diethyl ether; hexane / 30 h / 20 °C

3.2: 81 percent / pyridine; bromine / diethyl ether; hexane; CH₂Cl₂ / 0.5 h / -78 °C

4.1: BuLi / tetrahydrofuran; hexane / -78 °C

4.2: tetrahydrofuran; hexane / -78 °C

With n-butyllithium; diisobutylaluminium hydride; toluene-4-sulfonic acid; In tetrahydrofuran; diethyl ether; hexane; dichloromethane;
DOI:10.1021/jo026006j

Reference yield:

: 198411-16-4
(E)-5-bromo-5-dimethylphenylsilyl-1-(2-tetrahydropyranyloxy)-4-pentene

: 198411-17-5
1-((3-iodopropoxy)methyl)-4-methoxybenzene

: 460752-67-4
(Z)-5-dimethylphenylsilyl-8-p-methoxybenzyloxy-1-(2-tetrahydropyranyloxy)-4-octene

Guidance literature:: (E)-5-bromo-5-dimethylphenylsilyl-1-(2-tetrahydropyranyloxy)-4-pentene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃;

1-((3-iodopropoxy)methyl)-4-methoxybenzene; In tetrahydrofuran; hexane; at -78 ℃; Further stages.;
DOI:10.1021/jo026006j