(3S,4S)-N-carbamoyl-3-(4-phenoxybenzene-sulfonamido)-4-mercaptopyrrolidine

Base Information

Chemical Name:(3S,4S)-N-carbamoyl-3-(4-phenoxybenzene-sulfonamido)-4-mercaptopyrrolidine
CAS No.:1214272-29-3
Molecular Formula:C₁₇H₁₉N₃O₄S₂
Molecular Weight:393.488
Hs Code.:

Synonyms:(3S,4S)-N-carbamoyl-3-(4-phenoxybenzene-sulfonamido)-4-mercaptopyrrolidine

Suppliers and Price of (3S,4S)-N-carbamoyl-3-(4-phenoxybenzene-sulfonamido)-4-mercaptopyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of (3S,4S)-N-carbamoyl-3-(4-phenoxybenzene-sulfonamido)-4-mercaptopyrrolidine

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of (3S,4S)-N-carbamoyl-3-(4-phenoxybenzene-sulfonamido)-4-mercaptopyrrolidine

There total 6 articles about (3S,4S)-N-carbamoyl-3-(4-phenoxybenzene-sulfonamido)-4-mercaptopyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1214272-59-9
(3S,4S)-N-carbamoyl-3-(4-phenoxybenzenesulfonamido)-4-(2-nitrobenzenedisulfido)pyrrolidine

: 1214272-29-3
(3S,4S)-N-carbamoyl-3-(4-phenoxybenzene-sulfonamido)-4-mercaptopyrrolidine

Guidance literature:: With tris(2-carboxyethyl)phosphine; sodium hydroxide; In tetrahydrofuran; at 20 ℃; for 3h; Inert atmosphere;

Reference yield:

: 1623-92-3
4-phenoxyphenylsulfonyl chloride

: 1214272-29-3
(3S,4S)-N-carbamoyl-3-(4-phenoxybenzene-sulfonamido)-4-mercaptopyrrolidine

Guidance literature:: Multi-step reaction with 6 steps

1.1: triphenylphosphine; water / tetrahydrofuran / 20 - 65 °C

1.2: 0 - 20 °C

2.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 6 h / 20 °C

3.1: water; methylamine / methanol / 0.17 h / Inert atmosphere

4.1: dichloromethane / 2 h / 20 °C

5.1: trifluoroacetic acid / 20 °C

5.2: 0 - 20 °C

6.1: sodium hydroxide; tris(2-carboxyethyl)phosphine / tetrahydrofuran / 3 h / 20 °C / Inert atmosphere

With tris(2-carboxyethyl)phosphine; water; triphenylphosphine; methylamine; trifluoroacetic acid; sodium hydroxide; diethylazodicarboxylate; In tetrahydrofuran; methanol; dichloromethane;

Reference yield:

: 1214272-55-5
(3R,4S)-cis-N-Boc-3-hydroxy-4-(4-phenoxybenzenesulfonamido)pyrrolidine

: 1214272-29-3
(3S,4S)-N-carbamoyl-3-(4-phenoxybenzene-sulfonamido)-4-mercaptopyrrolidine

Guidance literature:: Multi-step reaction with 5 steps

1.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran / 6 h / 20 °C

2.1: water; methylamine / methanol / 0.17 h / Inert atmosphere

3.1: dichloromethane / 2 h / 20 °C

4.1: trifluoroacetic acid / 20 °C

4.2: 0 - 20 °C

5.1: sodium hydroxide; tris(2-carboxyethyl)phosphine / tetrahydrofuran / 3 h / 20 °C / Inert atmosphere

With tris(2-carboxyethyl)phosphine; water; triphenylphosphine; methylamine; trifluoroacetic acid; sodium hydroxide; diethylazodicarboxylate; In tetrahydrofuran; methanol; dichloromethane;