1-(3-Fluorophenyl)prop-2-yn-1-ol

Base Information

Chemical Name:1-(3-Fluorophenyl)prop-2-yn-1-ol
CAS No.:2107-40-6
Molecular Formula:C₉H₇FO
Molecular Weight:150.152
Hs Code.:
DSSTox Substance ID:DTXSID801300946
Mol file:2107-40-6.mol

Synonyms:1-(3-fluorophenyl)prop-2-yn-1-ol;2107-40-6;1-(3-Fluorophenyl)-2-propyn-1-ol;MFCD21143266;SCHEMBL10837272;DTXSID801300946;CAA10740;AKOS014245929;AB90770;AS-41190;SY045264;CS-0449450

Suppliers and Price of 1-(3-Fluorophenyl)prop-2-yn-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
1-(3-Fluorophenyl)prop-2-yn-1-ol
1g
$ 593.00

Matrix Scientific
1-(3-Fluorophenyl)prop-2-yn-1-ol
500mg
$ 376.00

Matrix Scientific
1-(3-Fluorophenyl)prop-2-yn-1-ol
5g
$ 1800.00

Crysdot
1-(3-Fluorophenyl)prop-2-yn-1-ol 95+%
1g
$ 395.00

Chemenu
1-(3-Fluorophenyl)-2-propyn-1-ol 95%
1g
$ 458.00

Alichem
1-(3-Fluorophenyl)prop-2-yn-1-ol
1g
$ 446.00

Alichem
1-(3-Fluorophenyl)prop-2-yn-1-ol
250mg
$ 181.56

Alichem
1-(3-Fluorophenyl)prop-2-yn-1-ol
5g
$ 1561.00

AK Scientific
1-(3-Fluorophenyl)prop-2-yn-1-ol
1g
$ 802.00

ACHEMBLOCK
1-(3-fluorophenyl)prop-2-yn-1-ol 95%
5G
$ 1740.00

Total 6 raw suppliers

Chemical Property of 1-(3-Fluorophenyl)prop-2-yn-1-ol

Chemical Property:

Boiling Point:66-68 °C(Press: 0.3 Torr)
PKA:12.12±0.20(Predicted)
Density:1.1642 g/cm3
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:150.048093005
Heavy Atom Count:11
Complexity:170

Purity/Quality:

97% ^*data from raw suppliers

1-(3-Fluorophenyl)prop-2-yn-1-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C#CC(C1=CC(=CC=C1)F)O

Technology Process of 1-(3-Fluorophenyl)prop-2-yn-1-ol

There total 7 articles about 1-(3-Fluorophenyl)prop-2-yn-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4301-14-8
acetylenemagnesium bromide

: 456-48-4
3-Fluorobenzaldehyde

: 2107-40-6,179249-17-3,179249-18-4
1-(3-fluorophenyl)-2-propyn-1-ol

Guidance literature:: at -78 - 0 ℃; Yield given;
DOI:10.1016/0957-4166(96)00166-8

Reference yield:

: 1-(3-fluorophenyl)-3-(trimethylsilyl)prop-2-yn-1-ol

: 2107-40-6,179249-17-3,179249-18-4
1-(3-fluorophenyl)-2-propyn-1-ol

Guidance literature:: With potassium carbonate; In methanol; at 0 ℃; for 1h; Inert atmosphere;

Reference yield:

: 456-48-4
3-Fluorobenzaldehyde

: 2107-40-6,179249-17-3,179249-18-4
1-(3-fluorophenyl)-2-propyn-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / 0 °C / Inert atmosphere

1.2: 2 h / 0 °C

2.1: potassium carbonate / methanol / 1 h / 0 °C / Inert atmosphere

With n-butyllithium; potassium carbonate; In tetrahydrofuran; methanol; hexane;