(5H-benzo[b]carbazol-6-yl)(4-methoxyphenyl)methanone

Base Information

• Chemical Name: (5H-benzo[b]carbazol-6-yl)(4-methoxyphenyl)methanone
• CAS No.: 1229244-51-2
• Molecular Formula: C₂₄H₁₇NO₂
• Molecular Weight: 351.404
• Mol file: 1229244-51-2.mol

Synonyms:(5H-benzo[b]carbazol-6-yl)(4-methoxyphenyl)methanone

Chemical Property of (5H-benzo[b]carbazol-6-yl)(4-methoxyphenyl)methanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (5H-benzo[b]carbazol-6-yl)(4-methoxyphenyl)methanone

There total 3 articles about (5H-benzo[b]carbazol-6-yl)(4-methoxyphenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

indole (120-72-9) + 2-(4-methoxyphenylethynyl)benzaldehyde (176910-67-1) → (5H-benzo[b]carbazol-6-yl)(4-methoxyphenyl)methanone (1229244-51-2)

Guidance literature:

With palladium dichloride; In 1-methyl-pyrrolidin-2-one; dimethyl sulfoxide; at 120 ℃; for 10h;

DOI:10.1002/chem.201000133

Reference yield:

C31H29NO5 → (5H-benzo[b]carbazol-6-yl)(4-methoxyphenyl)methanone (1229244-51-2)

Guidance literature:

With water; iodine; In acetonitrile; at 50 ℃; for 2h; Inert atmosphere;

DOI:10.1039/c4ob00815d

Reference yield:

C23H22O5 → (5H-benzo[b]carbazol-6-yl)(4-methoxyphenyl)methanone (1229244-51-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: copper(II) bis(trifluoromethanesulfonate); C₄₆H₅₀N₄O₄S₂ / tert-butyl alcohol / 0.25 h / 0 °C / Inert atmosphere

1.2: 0 °C / Inert atmosphere

2.1: iodine; water / acetonitrile / 2 h / 50 °C / Inert atmosphere

With C₄₆H₅₀N₄O₄S₂; water; iodine; copper(II) bis(trifluoromethanesulfonate); In acetonitrile; tert-butyl alcohol; 1.1: |Friedel-Crafts Alkylation / 1.2: |Friedel-Crafts Alkylation;

DOI:10.1039/c4ob00815d

upstream raw materials:

indole

2-(4-methoxyphenylethynyl)benzaldehyde