N-(4-Chlorophenyl)-1H-indole-3-carboxamide

Base Information

Chemical Name:N-(4-Chlorophenyl)-1H-indole-3-carboxamide
CAS No.:26977-44-6
Molecular Formula:C₁₅H₁₁ClN₂O
Molecular Weight:270.718
Hs Code.:
DSSTox Substance ID:DTXSID90589632
Wikidata:Q82483107

Synonyms:N-(4-Chlorophenyl)-1H-indole-3-carboxamide;26977-44-6;SCHEMBL20567521;DTXSID90589632;AKOS005887467;Z87529081

Suppliers and Price of N-(4-Chlorophenyl)-1H-indole-3-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
N-(4-Chlorophenyl)-1H-indole-3-carboxamide 95+%
5g
$ 628.00

Chemenu
N-(4-chlorophenyl)-1H-indole-3-carboxamide 95%
5g
$ 593.00

Alichem
N-(4-Chlorophenyl)-1H-indole-3-carboxamide
1g
$ 400.00

Total 2 raw suppliers

Chemical Property of N-(4-Chlorophenyl)-1H-indole-3-carboxamide

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:270.0559907
Heavy Atom Count:19
Complexity:328

Purity/Quality:

95+% ^*data from raw suppliers

N-(4-Chlorophenyl)-1H-indole-3-carboxamide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=CN2)C(=O)NC3=CC=C(C=C3)Cl

Technology Process of N-(4-Chlorophenyl)-1H-indole-3-carboxamide

There total 7 articles about N-(4-Chlorophenyl)-1H-indole-3-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 120-72-9
indole

: 132401-91-3
3-(4-chlorophenyl)-1,4,2-dioxazol-5-one

: 26977-44-6
N³-(4-chlorophenyl)-1H-indole-3-carboxamide

Guidance literature:: With potassium tert-butylate; In toluene; at 110 ℃; Inert atmosphere;
DOI:10.1055/s-0041-1737338

Reference yield: 75.0%

: 5457-28-3
3-cyano-1H-indole

: 1204518-00-2
(4-chlorophenyl)(mesityl)iodonium trifluoromethanesulfonate

: 26977-44-6
N³-(4-chlorophenyl)-1H-indole-3-carboxamide

Guidance literature:: With copper(II) bis(trifluoromethanesulfonate); In water; 1,2-dichloro-ethane; at 80 ℃; for 12h; chemoselective reaction; Inert atmosphere;
DOI:10.1039/d0ob02247k

Reference yield:

: 771-50-6
1H-indole-3-carboxylic acid

: 26977-44-6
N³-(4-chlorophenyl)-1H-indole-3-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: PCl₃ / toluene; acetonitrile / 0.42 h / 20 °C

2: toluene / 3 h / 20 °C

With phosphorus trichloride; In toluene; acetonitrile;
DOI:10.1135/cccc20040453