N-(2-nitrophenyl)-1,4-dioxa-7,13-dithia-10-azacyclopentadecane

Base Information

• Chemical Name: N-(2-nitrophenyl)-1,4-dioxa-7,13-dithia-10-azacyclopentadecane
• CAS No.: 1310840-37-9
• Molecular Formula: C₁₆H₂₄N₂O₄S₂
• Molecular Weight: 372.51
• Mol file: 1310840-37-9.mol

Synonyms:N-(2-nitrophenyl)-1,4-dioxa-7,13-dithia-10-azacyclopentadecane

Chemical Property of N-(2-nitrophenyl)-1,4-dioxa-7,13-dithia-10-azacyclopentadecane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2-nitrophenyl)-1,4-dioxa-7,13-dithia-10-azacyclopentadecane

There total 1 articles about N-(2-nitrophenyl)-1,4-dioxa-7,13-dithia-10-azacyclopentadecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

10-aza-1,4-dioxa-7,13-dithiacyclopentadecane (150602-89-4) + ortho-nitrofluorobenzene (1493-27-2,127723-77-7) → N-(2-nitrophenyl)-1,4-dioxa-7,13-dithia-10-azacyclopentadecane (1310840-37-9)

Guidance literature:

With caesium carbonate; at 60 ℃; for 72h; Inert atmosphere;

DOI:10.1039/c002727h

Reference yield: 57.0%

N-(2-nitrophenyl)-1,4-dioxa-7,13-dithia-10-azacyclopentadecane (1310840-37-9) → N-(2-aminophenyl)-1,4-dioxa-7,13-dithia-10-azacyclopentadecane (1310841-83-8)

Guidance literature:

With tin(II) chloride dihdyrate; In ethanol; at 90 ℃; for 3h; Inert atmosphere;

DOI:10.1039/c002727h

Reference yield:

N-(2-nitrophenyl)-1,4-dioxa-7,13-dithia-10-azacyclopentadecane (1310840-37-9) → 9-{[2-(1,4-dioxa-7,13-dithia-10-azacyclopentadec-10-yl)phenyl]amino}benzo[b]quinolizinium chloride (1310842-80-8)

Guidance literature:

Multi-step reaction with 2 steps

1: tin(II) chloride hydrate / ethanol / 3 h / 90 °C / Inert atmosphere

2: ethanol / 72 h / Reflux; Inert atmosphere

With tin(II) chloride hydrate; In ethanol;

DOI:10.1002/ejoc.201100329

upstream raw materials:

10-aza-1,4-dioxa-7,13-dithiacyclopentadecane

ortho-nitrofluorobenzene

Downstream raw materials:

N-(2-aminophenyl)-1,4-dioxa-7,13-dithia-10-azacyclopentadecane

9-{[2-(1,4-dioxa-7,13-dithia-10-azacyclopentadec-10-yl)phenyl]amino}benzo[b]quinolizinium chloride