4-Bromo-7-methoxyisatin

Base Information

• Chemical Name: 4-Bromo-7-methoxyisatin
• CAS No.: 67303-38-2
• Molecular Formula: C₉H₆BrNO₃
• Molecular Weight: 256.056
• Hs Code.: 2933990090
• Mol file: 67303-38-2.mol

Synonyms:4-Bromo-7-methoxyisatin;

Chemical Property of 4-Bromo-7-methoxyisatin

Chemical Property:

• Refractive Index: 1.618
• PSA: 55.40000
• Density: 1.733 g/cm³
• LogP: 1.73050
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%min ^*data from raw suppliers

4-Bromo-7-methoxyindoline-2,3-dione 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Bromo-7-methoxyisatin

There total 1 articles about 4-Bromo-7-methoxyisatin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 4-bromo-7-methoxyindoline-2,3-dione (67303-38-2)

Guidance literature:

entspr. Anisidid 6, H2SO4;

Reference yield:

4-bromo-7-methoxyindoline-2,3-dione (67303-38-2) → 2-amino-5-bromo-3-methoxy-6-(2-methylpyridin-4-yl)benzoic acid (1616830-53-5)

Guidance literature:

Multi-step reaction with 3 steps

1: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium carbonate / 1,4-dioxane; water / 18 h / 95 °C

2: bromine / acetic acid / 23 h / 25 - 80 °C

3: sodium hydroxide; dihydrogen peroxide / water / 0.33 h / 0 °C

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; dihydrogen peroxide; bromine; potassium carbonate; sodium hydroxide; In 1,4-dioxane; water; acetic acid;

Downstream raw materials:

2-amino-5-bromo-3-methoxy-6-(2-methylpyridin-4-yl)benzoic acid