p-nitrobenzyl α-(4R-acetylthio-3S-methoxy-3-phenoxyacetamido-2-azetidinon-1-yl)-β-methylcrotonate

Base Information

Chemical Name:p-nitrobenzyl α-(4R-acetylthio-3S-methoxy-3-phenoxyacetamido-2-azetidinon-1-yl)-β-methylcrotonate
CAS No.:117509-06-5
Molecular Formula:C₂₆H₂₇N₃O₉S
Molecular Weight:557.581
Hs Code.:

Synonyms:p-nitrobenzyl α-(4R-acetylthio-3S-methoxy-3-phenoxyacetamido-2-azetidinon-1-yl)-β-methylcrotonate

Suppliers and Price of p-nitrobenzyl α-(4R-acetylthio-3S-methoxy-3-phenoxyacetamido-2-azetidinon-1-yl)-β-methylcrotonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of p-nitrobenzyl α-(4R-acetylthio-3S-methoxy-3-phenoxyacetamido-2-azetidinon-1-yl)-β-methylcrotonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of p-nitrobenzyl α-(4R-acetylthio-3S-methoxy-3-phenoxyacetamido-2-azetidinon-1-yl)-β-methylcrotonate

There total 2 articles about p-nitrobenzyl α-(4R-acetylthio-3S-methoxy-3-phenoxyacetamido-2-azetidinon-1-yl)-β-methylcrotonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 41625-65-4
4-nitrobenzyl(2S,4S,5R,6R)-3,3-dimethyl-7-oxo-6-phenoxyacetamido-1-aza-4-thiabicyclo<3.2.0>heptane-2-carboxylate 4-oxide

: 117509-06-5
p-nitrobenzyl α-(4R-acetylthio-3S-methoxy-3-phenoxyacetamido-2-azetidinon-1-yl)-β-methylcrotonate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.)tert-butyl hypochlorite / 1.)CH₂Cl₂, -30 deg C, 2.)CH₂Cl₂, methanol, -30 deg C, 1 h

2: 1.)trimethyl phosphite 2.)triethylamine / 1.)toluene, 96 deg C, 24 h 2.)ethyl acetate, 3 h

With tert-butylhypochlorite; triethylamine; phosphorous acid trimethyl ester;
DOI:10.1139/v88-225

Reference yield:

: 108-24-7
acetic anhydride

: 41625-70-1
p-nitrobenzyl 6α-methoxy-6β-phenoxyacetamidopenicillanate-1β-oxide

: 117509-06-5
p-nitrobenzyl α-(4R-acetylthio-3S-methoxy-3-phenoxyacetamido-2-azetidinon-1-yl)-β-methylcrotonate

Guidance literature:: With triethylamine; phosphorous acid trimethyl ester; Yield given. Multistep reaction; 1.)toluene, 96 deg C, 24 h 2.)ethyl acetate, 3 h;
DOI:10.1139/v88-225