(S)-3-(4-Hydroxyphenyl)-5-(methoxymethyl)-2-oxazolidinone

Base Information

Chemical Name:(S)-3-(4-Hydroxyphenyl)-5-(methoxymethyl)-2-oxazolidinone
CAS No.:135605-66-2
Molecular Formula:C₁₁H₁₃NO₄
Molecular Weight:223.229
Hs Code.:2934999090
Mol file:135605-66-2.mol

Synonyms:(S)-3-(4-Hydroxyphenyl)-5-(methoxymethyl)-2-oxazolidinone;(S)-3-(4-hydroxyphenyl)-5-(methoxymethyl)oxazolidin-2-one

Suppliers and Price of (S)-3-(4-Hydroxyphenyl)-5-(methoxymethyl)-2-oxazolidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of (S)-3-(4-Hydroxyphenyl)-5-(methoxymethyl)-2-oxazolidinone

Chemical Property:

Vapor Pressure:5.28E-06mmHg at 25°C
Boiling Point:370.2°C at 760 mmHg
PKA:10.23±0.30(Predicted)
Flash Point:177.7°C
PSA：59.00000
Density:1.283g/cm³
LogP:1.42880

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (S)-3-(4-Hydroxyphenyl)-5-(methoxymethyl)-2-oxazolidinone

There total 3 articles about (S)-3-(4-Hydroxyphenyl)-5-(methoxymethyl)-2-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: (R)-3-(4-(benzyloxy)phenyl)-5-(methoxymethyl)oxazolidin-2-one

: 73422-62-5,135605-66-2
3-(4-hydroxyphenyl)-5-(methoxymethyl)oxazolidin-2-one

Guidance literature:: With 5%-palladium/activated carbon; hydrogen; In ethanol; dichloromethane; at 20 ℃; for 12h;
DOI:10.1039/c2cc32757k

Reference yield:

: 693830-78-3
methyl (4-(benzyloxy)phenyl)carbamate

: 73422-62-5,135605-66-2
3-(4-hydroxyphenyl)-5-(methoxymethyl)oxazolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 3 h / 155 °C / Inert atmosphere

2: 5%-palladium/activated carbon; hydrogen / ethanol; dichloromethane / 12 h / 20 °C

With 5%-palladium/activated carbon; hydrogen; potassium carbonate; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/c2cc32757k

Reference yield:

: 51388-20-6
4-benzyloxyaniline hydrochloride

: 73422-62-5,135605-66-2
3-(4-hydroxyphenyl)-5-(methoxymethyl)oxazolidin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / dichloromethane / 8 h / 20 °C / Inert atmosphere

2: potassium carbonate / N,N-dimethyl-formamide / 3 h / 155 °C / Inert atmosphere

3: 5%-palladium/activated carbon; hydrogen / ethanol; dichloromethane / 12 h / 20 °C

With 5%-palladium/activated carbon; hydrogen; potassium carbonate; triethylamine; In ethanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/c2cc32757k