1-[3-[[1-(benzoylamino)-3-methylbutyl]diphenylsilyl]-2-methyl-1-oxopropyl] L-proline 1,1-dimethylethyl ester

Base Information

Chemical Name:1-[3-[[1-(benzoylamino)-3-methylbutyl]diphenylsilyl]-2-methyl-1-oxopropyl] L-proline 1,1-dimethylethyl ester
CAS No.:207554-41-4
Molecular Formula:C₃₇H₄₈N₂O₄Si
Molecular Weight:612.885
Hs Code.:

Synonyms:1-[3-[[1-(benzoylamino)-3-methylbutyl]diphenylsilyl]-2-methyl-1-oxopropyl] L-proline 1,1-dimethylethyl ester

Suppliers and Price of 1-[3-[[1-(benzoylamino)-3-methylbutyl]diphenylsilyl]-2-methyl-1-oxopropyl] L-proline 1,1-dimethylethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-[3-[[1-(benzoylamino)-3-methylbutyl]diphenylsilyl]-2-methyl-1-oxopropyl] L-proline 1,1-dimethylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-[3-[[1-(benzoylamino)-3-methylbutyl]diphenylsilyl]-2-methyl-1-oxopropyl] L-proline 1,1-dimethylethyl ester

There total 2 articles about 1-[3-[[1-(benzoylamino)-3-methylbutyl]diphenylsilyl]-2-methyl-1-oxopropyl] L-proline 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 2812-46-6
proline tert-butyl ester

: 207554-37-8
3-[[1-(benzoylamino)-3-methylbutyl]diphenylsilyl]-2-methylpropionic acid

: 207554-41-4
1-[3-[[1-(benzoylamino)-3-methylbutyl]diphenylsilyl]-2-methyl-1-oxopropyl] L-proline 1,1-dimethylethyl ester

Guidance literature:: With dacarbazine;
DOI:10.1002/(SICI)1521-3773(19980403)37:6<812::AID-ANIE812>3.0.CO;2-I

Reference yield:

: 202743-39-3
3-[[1-(benzoylamino)-1-(3-methylbutyl)]diphenylsilyl] propanoic acid

: 207554-41-4
1-[3-[[1-(benzoylamino)-3-methylbutyl]diphenylsilyl]-2-methyl-1-oxopropyl] L-proline 1,1-dimethylethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: LDA / tetrahydrofuran; hexane / 1 h / 0 °C

1.2: 89 percent / tetrahydrofuran; hexane / 2 h / -78 °C

2.1: DIC; HOBt / CH₂Cl₂ / 0.08 h / 0 °C

2.2: 56 percent / CH₂Cl₂ / 14 h / 0 - 20 °C

With benzotriazol-1-ol; dacarbazine; lithium diisopropyl amide; In tetrahydrofuran; hexane; dichloromethane;
DOI:10.1021/ja026158w