5-oxo-5-((1-phenethylpiperidin-4-yl)(phenyl)amino)pentanoic acid

Base Information

• Chemical Name: 5-oxo-5-((1-phenethylpiperidin-4-yl)(phenyl)amino)pentanoic acid
• CAS No.: 526191-19-5
• Molecular Formula: C₂₄H₃₀N₂O₃
• Molecular Weight: 394.514
• Mol file: 526191-19-5.mol

Synonyms:5-oxo-5-((1-phenethylpiperidin-4-yl)(phenyl)amino)pentanoic acid

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Chemical Property of 5-oxo-5-((1-phenethylpiperidin-4-yl)(phenyl)amino)pentanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-oxo-5-((1-phenethylpiperidin-4-yl)(phenyl)amino)pentanoic acid

There total 9 articles about 5-oxo-5-((1-phenethylpiperidin-4-yl)(phenyl)amino)pentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methyl 5-oxo-5-((1-phenethylpiperidin-4-yl)(phenyl)amino)pentanoate → 5-oxo-5-((1-phenethylpiperidin-4-yl)(phenyl)amino)pentanoic acid (526191-19-5)

Guidance literature:

With lithium hydroxide; In methanol; water; at 20 ℃; for 4h;

DOI:10.1002/anie.201511654

Reference yield: 87.0%

glutaric anhydride, (108-55-4) + (1-Phenethyl-piperidin-4-yl)-phenyl-amine (21409-26-7) → 5-oxo-5-((1-phenethylpiperidin-4-yl)(phenyl)amino)pentanoic acid (526191-19-5)

Guidance literature:

With acetic acid; In dichloromethane; for 5h; Sealed tube; Heating;

DOI:10.1002/jhet.2696

Reference yield: 76.0%

methyl 5-oxo-5-(phenyl(piperidin-4-yl)amino)pentanoate + phenylacetaldehyde (122-78-1) → 5-oxo-5-((1-phenethylpiperidin-4-yl)(phenyl)amino)pentanoic acid (526191-19-5)

Guidance literature:

methyl 5-oxo-5-(phenyl(piperidin-4-yl)amino)pentanoate; phenylacetaldehyde; With sodium tris(acetoxy)borohydride; acetic acid; In 1,2-dichloro-ethane;

With water; lithium hydroxide; In methanol;

upstream raw materials:

glutaric anhydride,

(1-Phenethyl-piperidin-4-yl)-phenyl-amine

methyl 4-(chlorocarbonyl)butyrate

1-(tert-butoxycarbonyl)-4-phenylaminopiperidine

Downstream raw materials:

C₂₄H₂₉N₂O₂⁽¹⁺⁾*ClHO₄*ClO₄^(1-)

tryptophan 3,5-bis(trifluoromethyl)benzyl ester 5-oxo-5-((1-phenethylpiperidin-4-yl)(phenyl)amino)pentanoate

N₁-[2-(cyclohexylamino)-2-oxo-1-phenylethyl]-N₁,N₅-diphenyl-N₅-[1-(2-phenylethyl)piperidin-4-yl]pentanediamide

N₁-(4-bromophenyl)-N₁-[2-(cyclohexylamino)-2-oxo-1-phenylethyl]-N₅-phenyl-N₅-[1-(2-phenylethyl)piperidin-4-yl]pentanediamide