2-iodobenzene-1,4-disulfonic acid

Base Information

• Chemical Name: 2-iodobenzene-1,4-disulfonic acid
• CAS No.: 1282608-58-5
• Molecular Formula: C₆H₅IO₆S₂
• Molecular Weight: 364.139
• Mol file: 1282608-58-5.mol

Synonyms:2-iodobenzene-1,4-disulfonic acid

Chemical Property of 2-iodobenzene-1,4-disulfonic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-iodobenzene-1,4-disulfonic acid

There total 1 articles about 2-iodobenzene-1,4-disulfonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2-amino-1,4-benzenedisulfonic acid monosodium Salt (24605-36-5) → 2-iodobenzene-1,4-disulfonic acid (1282608-58-5)

Guidance literature:

2-amino-1,4-benzenedisulfonic acid monosodium Salt; With sodium carbonate; sodium nitrite; In water; at 0 ℃; for 0.5h;

With hydrogenchloride; In water; for 0.5h;

With potassium iodide; In water; at 0 - 80 ℃;

DOI:10.1016/j.bmc.2011.09.003

Reference yield: 54.0%

2-iodobenzene-1,4-disulfonic acid (1282608-58-5) → 2-iodobenzene-1,4-disulfonamide (1345021-18-2)

Guidance literature:

2-iodobenzene-1,4-disulfonic acid; With sodium hydroxide; In water; at 0 ℃;

With phosphorus pentachloride; at 80 ℃;

With ammonium hydroxide; In water; at 0 - 20 ℃; for 3h;

DOI:10.1016/j.bmc.2011.09.003

Reference yield:

2-iodobenzene-1,4-disulfonic acid (1282608-58-5) → 5-aminosulfonyl-3-(4-bromophenyl)-1,3,2-benzodithiazolium ylide 1,1-dioxide (1215268-36-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium hydroxide / water / 0 °C

1.2: 80 °C

1.3: 3 h / 0 - 20 °C

2.1: copper(l) iodide; potassium phosphate; 2.9-dimethyl-1,10-phenanthroline / toluene / 8 h / Inert atmosphere; Reflux

3.1: bromine / methanol; water / 0.5 h / 20 °C

With potassium phosphate; copper(l) iodide; 2.9-dimethyl-1,10-phenanthroline; bromine; sodium hydroxide; In methanol; water; toluene;

DOI:10.1016/j.bmc.2011.09.003

upstream raw materials:

2-amino-1,4-benzenedisulfonic acid monosodium Salt

Downstream raw materials:

5-aminosulfonyl-3-(4-bromophenyl)-1,3,2-benzodithiazolium ylide 1,1-dioxide

5-aminosulfonyl-3-(3-bromophenyl)-1,3,2-benzodithiazolium ylide 1,1-dioxide

5-aminosulfonyl-3-(4-fluorophenyl)-1,3,2-benzodithiazolium ylide 1,1-dioxide

5-aminosulfonyl-3-(4-chlorophenyl)-1,3,2-benzodithiazolium ylide 1,1-dioxide