2-(4-Benzyl-piperazin-1-YL-methyl)aniline

Base Information

Chemical Name:2-(4-Benzyl-piperazin-1-YL-methyl)aniline
CAS No.:60261-53-2
Molecular Formula:C18H23 N3
Molecular Weight:281.401
Hs Code.:2933599090
DSSTox Substance ID:DTXSID60455537
Mol file:60261-53-2.mol

Synonyms:60261-53-2;2-(4-BENZYL-PIPERAZIN-1-YL-METHYL)ANILINE;2-[(4-benzylpiperazin-1-yl)methyl]aniline;Benzenamine,2-[[4-(phenylmethyl)-1-piperazinyl]methyl]-;2-((4-benzylpiperazin-1-yl)methyl)aniline;DTXSID60455537;AKOS000163456;2-(4-benzylpiperazin-1-ylmethyl)aniline;A8417;FT-0604239

Suppliers and Price of 2-(4-Benzyl-piperazin-1-YL-methyl)aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(4-BENZYL-PIPERAZIN-1-YL-METHYL)ANILINE 95.00%
5MG
$ 502.10

Total 7 raw suppliers

Chemical Property of 2-(4-Benzyl-piperazin-1-YL-methyl)aniline

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:429.41°C at 760 mmHg
PKA:6.76±0.10(Predicted)
Flash Point:210.118°C
PSA：32.50000
Density:1.137g/cm³
LogP:3.04360
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:281.189197746
Heavy Atom Count:21
Complexity:293

Purity/Quality:

97% ^*data from raw suppliers

2-(4-BENZYL-PIPERAZIN-1-YL-METHYL)ANILINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1CC2=CC=CC=C2)CC3=CC=CC=C3N

Technology Process of 2-(4-Benzyl-piperazin-1-YL-methyl)aniline

There total 4 articles about 2-(4-Benzyl-piperazin-1-YL-methyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 414874-99-0
1-benzyl-4-(2-nitro-benzyl)-piperazine

: 60261-53-2
2-(4-benzyl-piperazin-1-ylmethyl)-aniline

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethyl acetate; at 20 ℃; under 2585.81 Torr;
DOI:10.1021/jm0201767

Reference yield:

: 2759-28-6
1-phenylmethylpiperazine

: 60261-53-2
2-(4-benzyl-piperazin-1-ylmethyl)-aniline

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / dimethylformamide / 20 °C

2: H₂ / Pd/C / ethyl acetate / 20 °C / 2585.81 Torr

With hydrogen; potassium carbonate; palladium on activated charcoal; In ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/jm0201767

Reference yield:

: 3958-60-9
2-nitrophenylmethyl bromide

: 60261-53-2
2-(4-benzyl-piperazin-1-ylmethyl)-aniline

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / dimethylformamide / 20 °C

2: H₂ / Pd/C / ethyl acetate / 20 °C / 2585.81 Torr

With hydrogen; potassium carbonate; palladium on activated charcoal; In ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/jm0201767