3-<<(benzyloxycarbonyl)glycyl>amino>-6-chloro-4-(2-chlorophenyl)-3,4-dihydro-4-hydroxy-2-methylquinazoline

Base Information

Chemical Name:3-<<(benzyloxycarbonyl)glycyl>amino>-6-chloro-4-(2-chlorophenyl)-3,4-dihydro-4-hydroxy-2-methylquinazoline
CAS No.:83520-05-2
Molecular Formula:C₂₅H₂₂Cl₂N₄O₄
Molecular Weight:513.38
Hs Code.:

Synonyms:3-<<(benzyloxycarbonyl)glycyl>amino>-6-chloro-4-(2-chlorophenyl)-3,4-dihydro-4-hydroxy-2-methylquinazoline

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Chemical Property of 3-<<(benzyloxycarbonyl)glycyl>amino>-6-chloro-4-(2-chlorophenyl)-3,4-dihydro-4-hydroxy-2-methylquinazoline

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Technology Process of 3-<<(benzyloxycarbonyl)glycyl>amino>-6-chloro-4-(2-chlorophenyl)-3,4-dihydro-4-hydroxy-2-methylquinazoline

There total 4 articles about 3-<<(benzyloxycarbonyl)glycyl>amino>-6-chloro-4-(2-chlorophenyl)-3,4-dihydro-4-hydroxy-2-methylquinazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 33.0%

: 5680-83-1
N-(benzyloxycarbonyl)glycine hydrazide

: 83520-07-4
2-thioacetamido-2',5-dichlorobenzophenone

: 83520-05-2
3-<<(benzyloxycarbonyl)glycyl>amino>-6-chloro-4-(2-chlorophenyl)-3,4-dihydro-4-hydroxy-2-methylquinazoline

Guidance literature:: With acetic acid; In ethanol; for 14h; Ambient temperature;
DOI:10.1021/jm00354a015

Reference yield: 17.0%

: 5680-83-1
N-(benzyloxycarbonyl)glycine hydrazide

: 54567-69-0
N-[4-Chloro-2-(2-chloro-benzoyl)-phenyl]-acetimidic acid ethyl ester

: 83520-05-2
3-<<(benzyloxycarbonyl)glycyl>amino>-6-chloro-4-(2-chlorophenyl)-3,4-dihydro-4-hydroxy-2-methylquinazoline

Guidance literature:: With acetic acid; In ethanol; for 6h; Ambient temperature;
DOI:10.1021/jm00354a015

Reference yield:

: 2958-36-3,53960-29-5
(2-amino-5-chloro-phenyl)-(2-chloro-phenyl)-methanone

: 83520-05-2
3-<<(benzyloxycarbonyl)glycyl>amino>-6-chloro-4-(2-chlorophenyl)-3,4-dihydro-4-hydroxy-2-methylquinazoline

Guidance literature:: Multi-step reaction with 2 steps

2: 17 percent / AcOH / ethanol / 6 h / Ambient temperature

With acetic acid; In ethanol;
DOI:10.1021/jm00354a015