(S)-BoroAla-(-)-Pinanediol-HCl

Base Information

• Chemical Name: (S)-BoroAla-(-)-Pinanediol-HCl
• CAS No.: 858354-78-6
• Molecular Formula: C₁₂H₂₂BNO₂*ClH
• Molecular Weight: 259.584
• Mol file: 858354-78-6.mol

Synonyms:4,6-Methano-1,3,2-benzodioxaborole-2-methanamine,hexahydro-a,3a,5,5-tetramethyl-, hydrochloride, (aS,3aS,4S,6S,7aR)-(9CI)

Chemical Property of (S)-BoroAla-(-)-Pinanediol-HCl

Chemical Property:

• PSA: 44.48000
• LogP: 3.52330

Purity/Quality:

97% ^*data from raw suppliers

(S)-BOROALA-(-)-PINANEDIOL-HCL 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-BoroAla-(-)-Pinanediol-HCl

There total 13 articles about (S)-BoroAla-(-)-Pinanediol-HCl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

(+)-pinanediol (1R)-1-(N,N-bis(trimethylsilyl)amino)-1-ethaneboronate → (R)-boroalanine-(1S,2S,3R,5S)-(+)-2,3-pinanediol ester hydrochloride (919103-31-4,858354-78-6)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; 1,4-dioxane; at -20 - 20 ℃; for 3h; Inert atmosphere;

Reference yield: 95.0%

C18H38BNO2Si2 (1313706-65-8) → (-)-pinanediol (1S)-(1-aminoethyl)-1-boronate hydrochloride (1265111-23-6,919103-31-4,858354-78-6)

Guidance literature:

With hydrogenchloride; In diethyl ether;

DOI:10.1021/ml100260x

Reference yield: 56.0%

C7H7BO2(CH3)3(CHClCH3) (87247-50-5) → (R)-boroalanine-(1S,2S,3R,5S)-(+)-2,3-pinanediol ester hydrochloride (919103-31-4,858354-78-6)

Guidance literature:

C₇H₇BO₂(CH₃)3(CHClCH₃); With potassium hexamethylsilazane; In tetrahydrofuran; at -20 - 23 ℃;

With hydrogenchloride; In 1,4-dioxane; hexane; at -10 - 23 ℃; Further stages.;

DOI:10.1016/j.tet.2007.03.033

upstream raw materials:

C₇H₇BO₂(CH₃)3(CHClCH₃)

pinanediol

(+)-α-pinene

(1S,2S,3R,5S)-2α,3α-pinanediol methylboronic ester

Downstream raw materials:

C₄₂H₆₁BClN₇O₇