3,4-di-O-benzyl-2-deoxy-D-erythro-pentose bisbenzyl dithioacetal

Base Information

• Chemical Name: 3,4-di-O-benzyl-2-deoxy-D-erythro-pentose bisbenzyl dithioacetal
• CAS No.: 134700-11-1
• Molecular Formula: C₃₃H₃₆O₃S₂
• Molecular Weight: 544.779
• Mol file: 134700-11-1.mol

Synonyms:3,4-di-O-benzyl-2-deoxy-D-erythro-pentose bisbenzyl dithioacetal

Chemical Property of 3,4-di-O-benzyl-2-deoxy-D-erythro-pentose bisbenzyl dithioacetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,4-di-O-benzyl-2-deoxy-D-erythro-pentose bisbenzyl dithioacetal

There total 4 articles about 3,4-di-O-benzyl-2-deoxy-D-erythro-pentose bisbenzyl dithioacetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

methyl 3,5-di-O-benzyl-2-deoxy-D-ribofuranoside (132487-16-2) + phenylmethanethiol (100-53-8) → 3,4-di-O-benzyl-2-deoxy-D-erythro-pentose bisbenzyl dithioacetal (134700-11-1)

Guidance literature:

With hydrogenchloride;

DOI:10.1016/j.carres.2005.07.011

Reference yield:

Methyl 3,5-di-O-benzyl-2-deoxy-D-erythropentoside (170984-20-0) + phenylmethanethiol (100-53-8) → 3,4-di-O-benzyl-2-deoxy-D-erythro-pentose bisbenzyl dithioacetal (134700-11-1)

Guidance literature:

With hydrogenchloride; In chloroform;

Reference yield:

D-2-deoxyribose (452-51-7,13046-70-3,29780-54-9,36792-87-7,36792-88-8,113890-35-0,113890-38-3) → 3,4-di-O-benzyl-2-deoxy-D-erythro-pentose bisbenzyl dithioacetal (134700-11-1)

Guidance literature:

Multi-step reaction with 3 steps

1: aq. HCl / 0.5 h / Ambient temperature

2: NaH, Bu₄NI / tetrahydrofuran / 60 h / Ambient temperature

3: 85 percent / conc. HCl / 18 h / 40 °C

With hydrogenchloride; tetra-(n-butyl)ammonium iodide; sodium hydride; In tetrahydrofuran;

DOI:10.1016/0008-6215(92)84165-O

upstream raw materials:

methyl 3,5-di-O-benzyl-2-deoxy-D-ribofuranoside

phenylmethanethiol

D-2-deoxyribose

1-O-methyl-2-deoxy-D-ribofuranoside

Downstream raw materials:

4-O-benzoyl-3,5-di-O-benzyl-2-deoxy-D-erythro-pentose dibenzyl dithioacetal

3,5-di-O-benzyl-2-deoxy-4-O-methanesulphonyl-D-erythro-pentose dibenzyl dithioacetal

4-O-benzoyl-3,5-di-O-benzyl-2-deoxy-L-threo-pentose dibenzyl dithioacetal

benzyl 3,5-di-O-benzyl-2-deoxy-1,4-dithio-α-threo-L-threo-pentofuranoside