methyl 4-[(5R,6R)-5-amino-6-hydroxy-6-phenylhex-1-en-1-yl]benzoate hydrochloride

Base Information

Chemical Name:methyl 4-[(5R,6R)-5-amino-6-hydroxy-6-phenylhex-1-en-1-yl]benzoate hydrochloride
CAS No.:1269615-25-9
Molecular Formula:C₂₀H₂₃NO₃*ClH
Molecular Weight:361.868
Hs Code.:

Synonyms:methyl 4-[(5R,6R)-5-amino-6-hydroxy-6-phenylhex-1-en-1-yl]benzoate hydrochloride

Suppliers and Price of methyl 4-[(5R,6R)-5-amino-6-hydroxy-6-phenylhex-1-en-1-yl]benzoate hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 4-[(5R,6R)-5-amino-6-hydroxy-6-phenylhex-1-en-1-yl]benzoate hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 4-[(5R,6R)-5-amino-6-hydroxy-6-phenylhex-1-en-1-yl]benzoate hydrochloride

There total 8 articles about methyl 4-[(5R,6R)-5-amino-6-hydroxy-6-phenylhex-1-en-1-yl]benzoate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 1269429-02-8
tert-butyl (4R,5R)-4-{4-[4-(methoxycarbonyl)phenyl]but-3-en-1-yl}-2,2-dimethyl-5-phenyl-1,3-oxazolidine-3-carboxylate

: 1269615-25-9
methyl 4-[(5R,6R)-5-amino-6-hydroxy-6-phenylhex-1-en-1-yl]benzoate hydrochloride

Guidance literature:: With hydrogenchloride; In methanol; at 20 ℃;
DOI:10.1016/j.bmcl.2015.11.030

Reference yield:

: tert-butyl (4S,5R)-4-formyl-2,2-dimethyl-5-phenyloxazolidine-3-carboxylate

: 1269615-25-9
methyl 4-[(5R,6R)-5-amino-6-hydroxy-6-phenylhex-1-en-1-yl]benzoate hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1.1: dichloromethane / 40 h / 20 °C

2.1: hydrogen / palladium 10% on activated carbon / acetone / 24 h / 20 °C

3.1: sodium t-butanolate / dimethyl sulfoxide / 0.75 h / 20 °C

3.2: 1.5 h / 20 °C

4.1: acetyl chloride; methanol / 5 h / 20 °C

With methanol; hydrogen; acetyl chloride; sodium t-butanolate; palladium 10% on activated carbon; In dichloromethane; dimethyl sulfoxide; acetone;

Reference yield:

: 1190391-87-7
tert-butyl (4R,5R)-2,2-dimethyl-4-[(1E)-3-oxoprop-1-en-1-yl]-5-phenyl-1,3-oxazolidine-3-carboxylate

: 1269615-25-9
methyl 4-[(5R,6R)-5-amino-6-hydroxy-6-phenylhex-1-en-1-yl]benzoate hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: hydrogen / palladium 10% on activated carbon / acetone / 24 h / 20 °C

2.1: sodium t-butanolate / dimethyl sulfoxide / 0.75 h / 20 °C

2.2: 1.5 h / 20 °C

3.1: acetyl chloride; methanol / 5 h / 20 °C

With methanol; hydrogen; acetyl chloride; sodium t-butanolate; palladium 10% on activated carbon; In dimethyl sulfoxide; acetone;