Acetic acid, [4-[3-[(6-amino-1,2,3,4-tetrahydro-2,4-dioxo-1,3-dipropyl-5-pyrimidinyl)amino]-2-methyl-3-oxopropyl]phenoxy]-, 1,1-dimethylethyl ester,

Base Information

Chemical Name:Acetic acid, [4-[3-[(6-amino-1,2,3,4-tetrahydro-2,4-dioxo-1,3-dipropyl-5-pyrimidinyl)amino]-2-methyl-3-oxopropyl]phenoxy]-, 1,1-dimethylethyl ester,
CAS No.:144872-05-9
Molecular Formula:C₂₆H₃₈N₄O₆
Molecular Weight:502.611
Hs Code.:
Mol file:144872-05-9.mol

Synonyms:Acetic acid, [4-[3-[(6-amino-1,2,3,4-tetrahydro-2,4-dioxo-1,3-dipropyl-5-pyrimidinyl)amino]-2-methyl-3-oxopropyl]phenoxy]-, 1,1-dimethylethyl ester, (-)-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Acetic acid, [4-[3-[(6-amino-1,2,3,4-tetrahydro-2,4-dioxo-1,3-dipropyl-5-pyrimidinyl)amino]-2-methyl-3-oxopropyl]phenoxy]-, 1,1-dimethylethyl ester,

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Technology Process of Acetic acid, [4-[3-[(6-amino-1,2,3,4-tetrahydro-2,4-dioxo-1,3-dipropyl-5-pyrimidinyl)amino]-2-methyl-3-oxopropyl]phenoxy]-, 1,1-dimethylethyl ester,

There total 2 articles about Acetic acid, [4-[3-[(6-amino-1,2,3,4-tetrahydro-2,4-dioxo-1,3-dipropyl-5-pyrimidinyl)amino]-2-methyl-3-oxopropyl]phenoxy]-, 1,1-dimethylethyl ester, which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 144871-76-1,144872-02-6,144872-06-0
4-[[2-(1,1-dimethylethoxy)-2-oxoethyl]oxy]-alpha-methyl-benzenepropanoic acid

: 81250-34-2
1,3-dipropyl-5,6-diaminouracil

: 543-27-1
isobutyl chloroformate

: 144871-77-2,144872-05-9,144872-07-1
2-[[4-[3-[(6-amino-1-propyl-1,2,3,4-tetrahydro-3-propyl-2,4-dioxo-5-pyrimidinyl)amino]-2-methyl-3-oxopropyl]phenyl]oxy]-acetic acid, 1,1-dimethylethyl ester

Guidance literature:: With 4-methyl-morpholine; In tetrahydrofuran; N-methyl-acetamide;

Reference yield:

: 144871-75-0,144872-03-7,144872-04-8
4-[[2-(1,1-dimethylethoxy)-2-oxoethyl]oxy]-alpha-methyl-benzenepropanoic acid, methyl ester

: 144871-77-2,144872-05-9,144872-07-1
2-[[4-[3-[(6-amino-1-propyl-1,2,3,4-tetrahydro-3-propyl-2,4-dioxo-5-pyrimidinyl)amino]-2-methyl-3-oxopropyl]phenyl]oxy]-acetic acid, 1,1-dimethylethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: lipase / diethyl ether

2: 4-methyl-morpholine / tetrahydrofuran; N-methyl-acetamide

With 4-methyl-morpholine; lipase; In tetrahydrofuran; N-methyl-acetamide; diethyl ether;