1-((1r,4r)-4-aminocyclohexyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carbonitrile hydrochloride

Base Information

Chemical Name:1-((1r,4r)-4-aminocyclohexyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carbonitrile hydrochloride
CAS No.:1456507-58-6
Molecular Formula:C₁₄H₁₆N₄O*ClH
Molecular Weight:292.768
Hs Code.:

Synonyms:1-((1r,4r)-4-aminocyclohexyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carbonitrile hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-((1r,4r)-4-aminocyclohexyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carbonitrile hydrochloride

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Technology Process of 1-((1r,4r)-4-aminocyclohexyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carbonitrile hydrochloride

There total 1 articles about 1-((1r,4r)-4-aminocyclohexyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carbonitrile hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 320407-60-1
tert-butyl ((1r,4r)-4-(5-cyano-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)cyclohexyl)carbamate

: 1456507-58-6
1-((1r,4r)-4-aminocyclohexyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carbonitrile hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; methanol; chloroform; at 0 - 20 ℃;

Reference yield:

: 4361-50-6
2-hydroxy-2-phenyl-propionaldehyde

: 1456507-58-6
1-((1r,4r)-4-aminocyclohexyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carbonitrile hydrochloride

: 1456507-59-7
1-((1r,4r)-4-((2-hydroxy-2-phenylpropyl)amino)cyclohexyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carbonitrile

Guidance literature:: 2-hydroxy-2-phenyl-propionaldehyde; 1-((1r,4r)-4-aminocyclohexyl)-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5-carbonitrile hydrochloride; With triethylamine; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

With sodium cyanoborohydride; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 2h;