tert-butyl cyclopentyl(3-(2-hydroxy-3-(isoindolin-2-yl)propoxy)benzyl)carbamate

Base Information

Chemical Name:tert-butyl cyclopentyl(3-(2-hydroxy-3-(isoindolin-2-yl)propoxy)benzyl)carbamate
CAS No.:1616059-88-1
Molecular Formula:C₂₈H₃₈N₂O₄
Molecular Weight:466.621
Hs Code.:

Synonyms:tert-butyl cyclopentyl(3-(2-hydroxy-3-(isoindolin-2-yl)propoxy)benzyl)carbamate

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Chemical Property of tert-butyl cyclopentyl(3-(2-hydroxy-3-(isoindolin-2-yl)propoxy)benzyl)carbamate

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Technology Process of tert-butyl cyclopentyl(3-(2-hydroxy-3-(isoindolin-2-yl)propoxy)benzyl)carbamate

There total 4 articles about tert-butyl cyclopentyl(3-(2-hydroxy-3-(isoindolin-2-yl)propoxy)benzyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 496-12-8
isoindoline

: 1616059-87-0
tert-butyl cyclopentyl(3-(oxiran-2-ylmethoxy)benzyl)carbamate

: 1616059-88-1
tert-butyl cyclopentyl(3-(2-hydroxy-3-(isoindolin-2-yl)propoxy)benzyl)carbamate

Guidance literature:: In ethanol; at 110 ℃; for 0.8h; Microwave irradiation;

Reference yield:

: 1616059-86-9
N-(3-(oxiran-2-ylmethoxy)benzyl)cyclopentanamine

: 1616059-88-1
tert-butyl cyclopentyl(3-(2-hydroxy-3-(isoindolin-2-yl)propoxy)benzyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran / 12 h / 20 °C

2: ethanol / 0.8 h / 110 °C / Microwave irradiation

With triethylamine; In tetrahydrofuran; ethanol;

Reference yield:

: 22590-64-3
3-(oxiran-2-ylmethoxy)benzaldehyde

: 1616059-88-1
tert-butyl cyclopentyl(3-(2-hydroxy-3-(isoindolin-2-yl)propoxy)benzyl)carbamate

Guidance literature:: Multi-step reaction with 3 steps

1.1: methanol / 4 h / 20 °C

1.2: 1 h

2.1: triethylamine / tetrahydrofuran / 12 h / 20 °C

3.1: ethanol / 0.8 h / 110 °C / Microwave irradiation

With triethylamine; In tetrahydrofuran; methanol; ethanol;