5-(cyanomethyl)-25,26,27,28-tetrakis<<(p-bromophenyl)sulfonyl>oxy>calix<4>arene

Base Information

• Chemical Name: 5-(cyanomethyl)-25,26,27,28-tetrakis<<(p-bromophenyl)sulfonyl>oxy>calix<4>arene
• CAS No.: 172534-25-7
• Molecular Formula: C₅₄H₃₇Br₄NO₁₂S₄
• Molecular Weight: 1339.77
• Mol file: 172534-25-7.mol

Synonyms:5-(cyanomethyl)-25,26,27,28-tetrakis<<(p-bromophenyl)sulfonyl>oxy>calix<4>arene

Chemical Property of 5-(cyanomethyl)-25,26,27,28-tetrakis<<(p-bromophenyl)sulfonyl>oxy>calix<4>arene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(cyanomethyl)-25,26,27,28-tetrakis<<(p-bromophenyl)sulfonyl>oxy>calix<4>arene

There total 1 articles about 5-(cyanomethyl)-25,26,27,28-tetrakis<<(p-bromophenyl)sulfonyl>oxy>calix<4>arene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

5-(Cyanomethyl)-25,26,27,28-tetrahydroxycalix[4]arene (157162-97-5) + 4-bromobenzenesulfonyl chloride (98-58-8) → 5-(cyanomethyl)-25,26,27,28-tetrakis<<(p-bromophenyl)sulfonyl>oxy>calix<4>arene (172534-25-7)

Guidance literature:

With sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide; paraffin; 1.) 5 min. r.t.; 2.) 18 h, r.t.;

DOI:10.1055/s-1995-4075

Reference yield: 95.0%

5-(cyanomethyl)-25,26,27,28-tetrakis<<(p-bromophenyl)sulfonyl>oxy>calix<4>arene (172534-25-7) → 5-(2-aminoethyl)-25,26,27,28-tetrakis<<(p-bromophenyl)sulfonyl>oxy>calix<4>arene

Guidance literature:

With diborane; In tetrahydrofuran; for 8h; Heating;

DOI:10.1021/jo981038l

Reference yield:

5-(cyanomethyl)-25,26,27,28-tetrakis<<(p-bromophenyl)sulfonyl>oxy>calix<4>arene (172534-25-7) → 5-ethyl-25,26,27,28-tetrakis<<(p-bromophenyl)sulfonyl>oxy>calix<4>arene

Guidance literature:

Multi-step reaction with 3 steps

1: H₂SO₄ / H₂O; acetic acid / 16 h / Heating

2: 87 percent / DCC, HOBt / CH₂Cl₂ / 8 h / Ambient temperature

3: 88 percent / B₂H₆ / tetrahydrofuran / 1 h / Ambient temperature

With sulfuric acid; benzotriazol-1-ol; dicyclohexyl-carbodiimide; diborane; In tetrahydrofuran; dichloromethane; water; acetic acid;

DOI:10.1021/jo981038l

upstream raw materials:

5-(Cyanomethyl)-25,26,27,28-tetrahydroxycalix[4]arene

4-bromobenzenesulfonyl chloride

Downstream raw materials:

5-(carboxymethyl)-25,26,27,28-tetrakis<<(p-bromophenyl)sulfonyl>oxy>calix<4>arene

5-(chlorocarbonylmethyl)-25,26,27,28-tetrakis<<(p-bromophenyl)sulfonyl>oxy>calix<4>arene

5-<(N,N-bis-2-<2-pyridyl>ethylamino)carbonyl>methyl-25,26,27,28-tetrakis<<(p-bromophenyl)sulfonyl>oxy>calix<4>arene

5-<(N,N-bis-2-<3,5-dimethylpyrazolyl>ethylamino)carbonyl>methyl-25,26,27,28-tetrakis<<(p-bromophenyl)sulfonyl>oxy>calix<4>arene