1-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl]-2-diphenylcarbamoyloxyimidazole

Base Information

Chemical Name:1-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl]-2-diphenylcarbamoyloxyimidazole
CAS No.:793674-25-6
Molecular Formula:C₄₂H₃₉N₃O₇
Molecular Weight:697.788
Hs Code.:

Synonyms:1-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl]-2-diphenylcarbamoyloxyimidazole

Suppliers and Price of 1-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl]-2-diphenylcarbamoyloxyimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl]-2-diphenylcarbamoyloxyimidazole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl]-2-diphenylcarbamoyloxyimidazole

There total 4 articles about 1-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl]-2-diphenylcarbamoyloxyimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 40615-36-9
4,4'-dimethoxytrityl chloride

: 793674-19-8
1-(2-deoxy-β-D-ribofuranosyl)-2-diphenylcarbamoyloxyimidazole

: 793674-25-6
1-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl]-2-diphenylcarbamoyloxyimidazole

Guidance literature:: With pyridine; at 20 ℃; for 12h;
DOI:10.1021/ja047201d

Reference yield:

: 500778-10-9
1-(2-deoxy-β-D-ribofuranosyl)imidazolin-2-one

: 793674-25-6
1-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl]-2-diphenylcarbamoyloxyimidazole

Guidance literature:: Multi-step reaction with 4 steps

1: 78 percent / pyridine / dimethylformamide / 12 h / 20 °C

2: 60 percent / N,N-diisopropylethylamine / pyridine / 12 h / 20 °C

3: 96 percent / Bu₄NF / tetrahydrofuran / 0.5 h / 20 °C

4: 86 percent / pyridine / 12 h / 20 °C

With pyridine; tetrabutyl ammonium fluoride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; pyridine; N,N-dimethyl-formamide;
DOI:10.1021/ja047201d

Reference yield:

: 793674-23-4
1-(2-deoxy-3,5-di-O-tetraisopropyldisiloxanyl-β-D-ribofuranosyl)imidazolin-2-one

: 793674-25-6
1-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-ribofuranosyl]-2-diphenylcarbamoyloxyimidazole

Guidance literature:: Multi-step reaction with 3 steps

1: 60 percent / N,N-diisopropylethylamine / pyridine / 12 h / 20 °C

2: 96 percent / Bu₄NF / tetrahydrofuran / 0.5 h / 20 °C

3: 86 percent / pyridine / 12 h / 20 °C

With pyridine; tetrabutyl ammonium fluoride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; pyridine;
DOI:10.1021/ja047201d