acetic acid 4-acetoxy-6-acetoxymethyl-2-(4-{1-(4-fluoro-phenyl)-3-[3-(4-fluoro-phenyl)-propyl]-4-oxo-azetidin-2-yl}-phenoxy)-5-(3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yl ester

Base Information

• Chemical Name: acetic acid 4-acetoxy-6-acetoxymethyl-2-(4-{1-(4-fluoro-phenyl)-3-[3-(4-fluoro-phenyl)-propyl]-4-oxo-azetidin-2-yl}-phenoxy)-5-(3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yl ester
• CAS No.: 795306-61-5
• Molecular Formula: C₅₀H₅₅F₂NO₁₉
• Molecular Weight: 1011.98

Synonyms:acetic acid 4-acetoxy-6-acetoxymethyl-2-(4-{1-(4-fluoro-phenyl)-3-[3-(4-fluoro-phenyl)-propyl]-4-oxo-azetidin-2-yl}-phenoxy)-5-(3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yl ester

Chemical Property of acetic acid 4-acetoxy-6-acetoxymethyl-2-(4-{1-(4-fluoro-phenyl)-3-[3-(4-fluoro-phenyl)-propyl]-4-oxo-azetidin-2-yl}-phenoxy)-5-(3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of acetic acid 4-acetoxy-6-acetoxymethyl-2-(4-{1-(4-fluoro-phenyl)-3-[3-(4-fluoro-phenyl)-propyl]-4-oxo-azetidin-2-yl}-phenoxy)-5-(3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yl ester

There total 8 articles about acetic acid 4-acetoxy-6-acetoxymethyl-2-(4-{1-(4-fluoro-phenyl)-3-[3-(4-fluoro-phenyl)-propyl]-4-oxo-azetidin-2-yl}-phenoxy)-5-(3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 23.0%

acetic acid 4-acetoxy-6-acetoxymethyl-2-(4-{1-(4-fluoro-phenyl)-3-[3-(4-fluoro-phenyl)-3-hydroxy-propyl]-4-oxo-azetidin-2-yl}-phenoxy)-5-(3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yl ester (795306-59-1) → acetic acid 4-acetoxy-6-acetoxymethyl-2-(4-{1-(4-fluoro-phenyl)-3-[3-(4-fluoro-phenyl)-propyl]-4-oxo-azetidin-2-yl}-phenoxy)-5-(3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yl ester (795306-61-5)

Guidance literature:

With hydrogen; palladium dihydroxide; In ethanol; ethyl acetate; for 29h;

DOI:10.1002/anie.200460348

Reference yield:

Acetic acid 4-[(2S,3R)-3-[(S)-3-(tert-butyl-dimethyl-silanyloxy)-3-(4-fluoro-phenyl)-propyl]-1-(4-fluoro-phenyl)-4-oxo-azetidin-2-yl]-phenyl ester (795306-55-7) → acetic acid 4-acetoxy-6-acetoxymethyl-2-(4-{1-(4-fluoro-phenyl)-3-[3-(4-fluoro-phenyl)-propyl]-4-oxo-azetidin-2-yl}-phenoxy)-5-(3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yl ester (795306-61-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 83 percent / neutral alumina / CH₂Cl₂ / 5.5 h / 70 °C

2: BF₃*OEt₂ / CH₂Cl₂ / 2.5 h / -37 - 20 °C

3: 23 percent / H₂ / Pd(OH)2/C / ethanol; ethyl acetate / 29 h

With aluminum oxide; boron trifluoride diethyl etherate; hydrogen; palladium dihydroxide; In ethanol; dichloromethane; ethyl acetate;

DOI:10.1002/anie.200460348

Reference yield:

Acetic acid 4-{(2S,3R)-1-(4-fluoro-phenyl)-3-[(S)-3-(4-fluoro-phenyl)-3-hydroxy-propyl]-4-oxo-azetidin-2-yl}-phenyl ester (795306-53-5) → acetic acid 4-acetoxy-6-acetoxymethyl-2-(4-{1-(4-fluoro-phenyl)-3-[3-(4-fluoro-phenyl)-propyl]-4-oxo-azetidin-2-yl}-phenoxy)-5-(3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yl ester (795306-61-5)

Guidance literature:

Multi-step reaction with 4 steps

1: 91 percent / imidazole / dimethylformamide / 3 h

2: 83 percent / neutral alumina / CH₂Cl₂ / 5.5 h / 70 °C

3: BF₃*OEt₂ / CH₂Cl₂ / 2.5 h / -37 - 20 °C

4: 23 percent / H₂ / Pd(OH)2/C / ethanol; ethyl acetate / 29 h

With 1H-imidazole; aluminum oxide; boron trifluoride diethyl etherate; hydrogen; palladium dihydroxide; In ethanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide;

DOI:10.1002/anie.200460348

upstream raw materials:

acetic acid 4-acetoxy-6-acetoxymethyl-2-(4-{1-(4-fluoro-phenyl)-3-[3-(4-fluoro-phenyl)-3-hydroxy-propyl]-4-oxo-azetidin-2-yl}-phenoxy)-5-(3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yl ester

Acetic acid 4-{(2S,3R)-1-(4-fluoro-phenyl)-3-[(S)-3-(4-fluoro-phenyl)-3-hydroxy-propyl]-4-oxo-azetidin-2-yl}-phenyl ester

3′-(S)-4-(S)-3-(R)-[3′-t-butyldimethylsilyloxy-3′-(4-fluorophenyl)propyl]-4-(4-hydroxyphenyl)-1-(4-fluorophenyl)azetidin-2-one

Acetic acid 4-[(2S,3R)-3-[(S)-3-(tert-butyl-dimethyl-silanyloxy)-3-(4-fluoro-phenyl)-propyl]-1-(4-fluoro-phenyl)-4-oxo-azetidin-2-yl]-phenyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 795306-61-5 acetic acid 4-acetoxy-6-acetoxymethyl-2-(4-{1-(4-fluoro-phenyl)-3-[3-(4-fluoro-phenyl)-propyl]-4-oxo-azetidin-2-yl}-phenoxy)-5-(3,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-2-yloxy)-tetrahydro-pyran-3-yl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send