Sudoxicam

Base Information

• Chemical Name: Sudoxicam
• CAS No.: 29152-10-1
• Molecular Formula: C₁₃H₁₁N₃O₄S₂
• Molecular Weight: 337.38
• Mol file: 29152-10-1.mol

Synonyms:(3Z)-3-[hydroxy(1,3-thiazol-2-ylamino)methylidene]-2-methyl-2,3-dihydro-4H-1,2-benzothiazin-4-one 1,1-dioxide; 4-hydroxy-2-methyl-N-(1,3-thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide

Chemical Property of Sudoxicam

Chemical Property:

• Refractive Index: 1.741
• PSA: 133.06000
• Density: 1.675g/cm³
• LogP: 2.05890

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Sudoxicam

There total 3 articles about Sudoxicam which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(2-thiazolyl)-N'-methyl-N'-(2'-methoxycarbonylbenzenesulfonyl)glycineamide → N-(2-Thiazolyl)-3,4-dihydro-2-methyl-4-oxo-2H-1,2-benzothiazin-3-carboxamid-1,1-dioxid (29152-10-1)

Guidance literature:

In tetrahydrofuran; hexane; chloroform;

Reference yield:

2-thiazolylamine (96-50-4) + acid chloride of 3,4-dihydro-2-methyl-4-oxo-2H-1,2-benzothiazine-3-carboxylic acid-1,1-dioxide (108964-50-7) → N-(2-Thiazolyl)-3,4-dihydro-2-methyl-4-oxo-2H-1,2-benzothiazin-3-carboxamid-1,1-dioxid (29152-10-1)

Guidance literature:

In methanol; N,N-dimethyl acetamide;

Reference yield:

→ N-(2-Thiazolyl)-3,4-dihydro-2-methyl-4-oxo-2H-1,2-benzothiazin-3-carboxamid-1,1-dioxid (29152-10-1)

Guidance literature:

4-Isopropoxy-Δ^3,4-Verb., HBr/H2O;

upstream raw materials:

2-thiazolylamine

acid chloride of 3,4-dihydro-2-methyl-4-oxo-2H-1,2-benzothiazine-3-carboxylic acid-1,1-dioxide

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