cis,anti-3-<1'-(Dimethylphenylsilyl)ethyl>-4-(methoxycarbonyl)azetidin-2-one

Base Information

Chemical Name:cis,anti-3-<1'-(Dimethylphenylsilyl)ethyl>-4-(methoxycarbonyl)azetidin-2-one
CAS No.:138235-13-9
Molecular Formula:C₁₅H₂₁NO₃Si
Molecular Weight:291.422
Hs Code.:

Synonyms:cis,anti-3-<1'-(Dimethylphenylsilyl)ethyl>-4-(methoxycarbonyl)azetidin-2-one

Suppliers and Price of cis,anti-3-<1'-(Dimethylphenylsilyl)ethyl>-4-(methoxycarbonyl)azetidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of cis,anti-3-<1'-(Dimethylphenylsilyl)ethyl>-4-(methoxycarbonyl)azetidin-2-one

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of cis,anti-3-<1'-(Dimethylphenylsilyl)ethyl>-4-(methoxycarbonyl)azetidin-2-one

There total 1 articles about cis,anti-3-<1'-(Dimethylphenylsilyl)ethyl>-4-(methoxycarbonyl)azetidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 138235-09-3
(2S,3S)-1-[Bis-(4-methoxy-phenyl)-methyl]-3-[(R)-1-(dimethyl-phenyl-silanyl)-ethyl]-4-oxo-azetidine-2-carboxylic acid methyl ester

: 138235-13-9
cis,anti-3-<1'-(Dimethylphenylsilyl)ethyl>-4-(methoxycarbonyl)azetidin-2-one

Guidance literature:: With ammonium cerium(IV) nitrate; In water; acetonitrile; at -10 ℃; for 3h;
DOI:10.1021/jo00031a044

Reference yield:

: 138235-13-9
cis,anti-3-<1'-(Dimethylphenylsilyl)ethyl>-4-(methoxycarbonyl)azetidin-2-one

: 138235-17-3
Methyl 2(S*)-(benzoylamino)-4(R*)-hydroxy-3(S*)-(methoxycarbonyl)pentanoate

Guidance literature:: Multi-step reaction with 4 steps

1: ClSiMe₃ / 4 h / Ambient temperature

2: NEt₃ / CH₂Cl₂ / 4 h / Ambient temperature

3: HBF₄*OEt₂ / CH₂Cl₂ / 1 h / Ambient temperature

4: peracetic acid, triethylamine / acetic acid / 3 h / Ambient temperature

With peracetic acid; tetrafluoroboric acid diethyl ether; chloro-trimethyl-silane; triethylamine; In dichloromethane; acetic acid;
DOI:10.1021/jo00031a044

Reference yield:

: 138235-13-9
cis,anti-3-<1'-(Dimethylphenylsilyl)ethyl>-4-(methoxycarbonyl)azetidin-2-one

: (2R,3R)-2-Benzoylamino-3-[(S)-1-(fluoro-dimethyl-silanyl)-ethyl]-succinic acid dimethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: ClSiMe₃ / 4 h / Ambient temperature

2: NEt₃ / CH₂Cl₂ / 4 h / Ambient temperature

3: HBF₄*OEt₂ / CH₂Cl₂ / 1 h / Ambient temperature

With tetrafluoroboric acid diethyl ether; chloro-trimethyl-silane; triethylamine; In dichloromethane;
DOI:10.1021/jo00031a044