(2S,4R)-1-benzyl-4-[(2,4-difluorobenzyl)-(2,2,2-trichloroethoxy carbonyl)-amino]pyrrolidine

Base Information

Chemical Name:(2S,4R)-1-benzyl-4-[(2,4-difluorobenzyl)-(2,2,2-trichloroethoxy carbonyl)-amino]pyrrolidine
CAS No.:1092099-63-2
Molecular Formula:C₂₂H₂₁Cl₃F₂N₂O₄
Molecular Weight:521.776
Hs Code.:

Synonyms:(2S,4R)-1-benzyl-4-[(2,4-difluorobenzyl)-(2,2,2-trichloroethoxy carbonyl)-amino]pyrrolidine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2S,4R)-1-benzyl-4-[(2,4-difluorobenzyl)-(2,2,2-trichloroethoxy carbonyl)-amino]pyrrolidine

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Technology Process of (2S,4R)-1-benzyl-4-[(2,4-difluorobenzyl)-(2,2,2-trichloroethoxy carbonyl)-amino]pyrrolidine

There total 1 articles about (2S,4R)-1-benzyl-4-[(2,4-difluorobenzyl)-(2,2,2-trichloroethoxy carbonyl)-amino]pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1092099-62-1
(2S,4R)-1-benzyl-4-[(2,4-difluorobenzyl)-(2,2,2-trichloroethoxy carbonyl)-amino]pyrrolidine methyl ester

: 1092099-63-2
(2S,4R)-1-benzyl-4-[(2,4-difluorobenzyl)-(2,2,2-trichloroethoxy carbonyl)-amino]pyrrolidine

Guidance literature:: With lithium hydroxide; In methanol;

Reference yield:

: 35386-24-4
1-(2-Methoxyphenyl)piperazine

: 1092099-63-2
(2S,4R)-1-benzyl-4-[(2,4-difluorobenzyl)-(2,2,2-trichloroethoxy carbonyl)-amino]pyrrolidine

: 1092099-64-3
{(2S,4R)-1-benzyl-4-[(2,4-difluorobenzyl)-2,2,2-trichloroethoxycarbonyl-amino]pyrrolidin-2-yl}-[4-(2-methoxy-phenyl)-piperazin-1-yl]methanone

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 20 ℃;