Technology Process of C27H42O4
There total 7 articles about C27H42O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triethylamine; lithium bromide;
In
tetrahydrofuran;
at 0 ℃;
for 16h;
Inert atmosphere;
DOI:10.1016/j.tetlet.2014.05.076
- Guidance literature:
-
Multi-step reaction with 3 steps
1: oxalyl dichloride; triethylamine / dimethyl sulfoxide / 1 h / -78 °C / Inert atmosphere
2: tin(ll) chloride / dichloromethane / 3 h / 20 °C / Inert atmosphere
3: triethylamine; lithium bromide / tetrahydrofuran / 16 h / 0 °C / Inert atmosphere
With
oxalyl dichloride; triethylamine; tin(ll) chloride; lithium bromide;
In
tetrahydrofuran; dichloromethane; dimethyl sulfoxide;
1: |Swern Oxidation;
DOI:10.1016/j.tetlet.2014.05.076
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: potassium tert-butylate; N,N,N,N,N,N-hexamethylphosphoric triamide / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere
1.2: 20 °C / Inert atmosphere
2.1: potassium carbonate / methanol / 3 h / 20 °C / Inert atmosphere
3.1: hydrogen / ethyl acetate / 3 h / 20 °C / Inert atmosphere
4.1: oxalyl dichloride; triethylamine / dimethyl sulfoxide / 1 h / -78 °C / Inert atmosphere
5.1: tin(ll) chloride / dichloromethane / 3 h / 20 °C / Inert atmosphere
6.1: triethylamine; lithium bromide / tetrahydrofuran / 16 h / 0 °C / Inert atmosphere
With
N,N,N,N,N,N-hexamethylphosphoric triamide; oxalyl dichloride; potassium tert-butylate; hydrogen; potassium carbonate; triethylamine; tin(ll) chloride; lithium bromide;
In
tetrahydrofuran; methanol; dichloromethane; dimethyl sulfoxide; ethyl acetate;
1.1: |Horner-Wadsworth-Emmons Olefination / 4.1: |Swern Oxidation;
DOI:10.1016/j.tetlet.2014.05.076
