4-bromo-3-ethoxybenzoic acid

Base Information

• Chemical Name: 4-bromo-3-ethoxybenzoic acid
• CAS No.: 933671-86-4
• Molecular Formula: C₉H₉BrO₃
• Molecular Weight: 245.073
• Mol file: 933671-86-4.mol

Synonyms:4-bromo-3-ethoxybenzoic acid

Chemical Property of 4-bromo-3-ethoxybenzoic acid

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

4-BROMO-3-ETHOXYBENZOICACID 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-bromo-3-ethoxybenzoic acid

There total 4 articles about 4-bromo-3-ethoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.3%

ethyl-4-bromo-3-ethoxybenzoate (220380-11-0) → 4-bromo-3-ethoxybenzoic acid (933671-86-4)

Guidance literature:

With water; sodium hydroxide; In methanol; at 20 ℃; for 10h;

Reference yield:

methyl 4-bromo-3-ethoxybenzoate (1041205-21-3) → 4-bromo-3-ethoxybenzoic acid (933671-86-4)

Guidance literature:

methyl 4-bromo-3-ethoxybenzoate; With water; lithium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 1h;

With hydrogenchloride; In tetrahydrofuran; methanol; water; pH=4;

Reference yield:

methyl 4-bromo-3-hydroxybenzoate (106291-80-9) → 4-bromo-3-ethoxybenzoic acid (933671-86-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: potassium carbonate / N,N-dimethyl-formamide / 16 h / 20 °C

2.1: water; lithium hydroxide / tetrahydrofuran; methanol / 1 h / 20 °C

2.2: pH 4

With water; potassium carbonate; lithium hydroxide; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;

upstream raw materials:

methyl 4-bromo-3-hydroxybenzoate

methyl 4-bromo-3-ethoxybenzoate

4-bromo-3-hydroxybenzoic acid

ethyl-4-bromo-3-ethoxybenzoate

Downstream raw materials:

4-bromo-3-ethoxy-N,N-diethylbenzamide