N~1~-[3-(trifluoromethyl)phenyl]-1,2-benzenediamine

Base Information

Chemical Name:N~1~-[3-(trifluoromethyl)phenyl]-1,2-benzenediamine
CAS No.:43034-86-2
Molecular Formula:C₁₃H₁₁F₃N₂
Molecular Weight:252.239
Hs Code.:
European Community (EC) Number:856-742-8
ChEMBL ID:CHEMBL1367786

Synonyms:43034-86-2;N1-[3-(trifluoromethyl)phenyl]benzene-1,2-diamine;N~1~-[3-(trifluoromethyl)phenyl]-1,2-benzenediamine;2-N-[3-(trifluoromethyl)phenyl]benzene-1,2-diamine;MLS000755670;SMR000337335;SCHEMBL4064881;CHEMBL1367786;BDBM83792;cid_3729763;HMS2590B21;MFCD05669422;AKOS005107528;MS-1076;CS-0243469;N-(3-trifluoromethylphenyl)benzene-1,2-diamine;(2-aminophenyl)-[3-(trifluoromethyl)phenyl]amine;EN300-26405907;SR-01000308311;N1-[3-(Trifluoromethyl)phenyl]-1,2-benzenediamine;N2-[3-(trifluoromethyl)phenyl]benzene-1,2-diamine;SR-01000308311-1;Z367655624

Suppliers and Price of N~1~-[3-(trifluoromethyl)phenyl]-1,2-benzenediamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of N~1~-[3-(trifluoromethyl)phenyl]-1,2-benzenediamine

Chemical Property:

XLogP3:4.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:252.08743285
Heavy Atom Count:18
Complexity:268

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C(=C1)N)NC2=CC=CC(=C2)C(F)(F)F

Technology Process of N~1~-[3-(trifluoromethyl)phenyl]-1,2-benzenediamine

There total 4 articles about N~1~-[3-(trifluoromethyl)phenyl]-1,2-benzenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 365-60-6
2-nitro-N-(3-(trifluoromethyl)phenyl)aniline

: 43034-86-2
N¹-(3-(trifluoromethyl)phenyl)benzene-1,2-diamine

Guidance literature:: With hydrogen; palladium on activated charcoal; In acetic acid;

Reference yield:

: 1493-27-2,127723-77-7
ortho-nitrofluorobenzene

: 43034-86-2
N¹-(3-(trifluoromethyl)phenyl)benzene-1,2-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium fluoride / 24 h / 140 °C

2: iron; hydrogenchloride; hydroxylamine hydrochloride / ethanol; water / 2 h / Reflux

With hydrogenchloride; potassium fluoride; hydroxylamine hydrochloride; iron; In ethanol; water;
DOI:10.1016/j.bmc.2018.04.029

Reference yield:

: 98-16-8
3-trifluoromethylaniline

: 43034-86-2
N¹-(3-(trifluoromethyl)phenyl)benzene-1,2-diamine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium fluoride / 24 h / 140 °C

2: iron; hydrogenchloride; hydroxylamine hydrochloride / ethanol; water / 2 h / Reflux

With hydrogenchloride; potassium fluoride; hydroxylamine hydrochloride; iron; In ethanol; water;
DOI:10.1016/j.bmc.2018.04.029