5-Ethyl-isoxazole-4-carboxylic acid

Base Information

Chemical Name:5-Ethyl-isoxazole-4-carboxylic acid
CAS No.:134541-03-0
Molecular Formula:C6H7NO3
Molecular Weight:141.12
Hs Code.:2934999090
European Community (EC) Number:804-981-3
DSSTox Substance ID:DTXSID90564025
Nikkaji Number:J396.794H
Wikidata:Q82448592
Mol file:134541-03-0.mol

Synonyms:134541-03-0;5-ETHYL-ISOXAZOLE-4-CARBOXYLIC ACID;5-Ethylisoxazole-4-carboxylic acid;5-Ethyl-1,2-oxazole-4-carboxylic acid;5-ethyl-4-isoxazolecarboxylic acid;4-Isoxazolecarboxylic acid, 5-ethyl-;SCHEMBL4145759;DTXSID90564025;5-Ethylisoxazole-4-carboxylicacid;MFCD07357474;AKOS009423790;AS-62297;CS-0120444;EN300-202739;5-ethyl-isoxazole-4-carboxylic acid, AldrichCPR;A854017;Z406694030

Suppliers and Price of 5-Ethyl-isoxazole-4-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Ethyl-Isoxazole-4-CarboxylicAcid
10mg
$ 45.00

Crysdot
5-Ethylisoxazole-4-carboxylicacid 95+%
1g
$ 340.00

Crysdot
5-Ethylisoxazole-4-carboxylicacid 95+%
5g
$ 1022.00

Chemenu
5-Ethylisoxazole-4-carboxylicacid 96%
5g
$ 963.00

Chemenu
5-Ethylisoxazole-4-carboxylicacid 96%
1g
$ 321.00

ChemBridge Corporation
5-ethyl-4-isoxazolecarboxylicacid 95%
250 mg
$ 170.00

American Custom Chemicals Corporation
5-ETHYL-ISOXAZOLE-4-CARBOXYLIC ACID 95.00%
5MG
$ 495.99

AK Scientific
5-Ethyl-isoxazole-4-carboxylicacid
5g
$ 1386.00

AK Scientific
5-Ethyl-isoxazole-4-carboxylicacid
100mg
$ 505.00

Total 12 raw suppliers

Chemical Property of 5-Ethyl-isoxazole-4-carboxylic acid

Chemical Property:

Vapor Pressure:0.001mmHg at 25°C
Melting Point:85-87 °C(Solv: ligroine (8032-32-4))
Refractive Index:1.509
Boiling Point:290.4°Cat760mmHg
PKA:2.81±0.10(Predicted)
Flash Point:129.4°C
PSA：63.33000
Density:1.273g/cm³
LogP:0.93520
XLogP3:0.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:141.042593085
Heavy Atom Count:10
Complexity:137

Purity/Quality:

97% ^*data from raw suppliers

5-Ethyl-Isoxazole-4-CarboxylicAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=C(C=NO1)C(=O)O

Technology Process of 5-Ethyl-isoxazole-4-carboxylic acid

There total 3 articles about 5-Ethyl-isoxazole-4-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 134540-94-6
ethyl 5-ethylisoxazole-4-carboxylate

: 134541-03-0
5-Ethyl-4-isoxazolecarboxylic acid

Guidance literature:: With hydrogenchloride; acetic acid; for 3h; Heating;

Reference yield:

: 89193-23-7
ethyl (E)-2-((dimethylamino)methylene)-3-oxopentanoate

: 134541-03-0
5-Ethyl-4-isoxazolecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / NH₂OH*HCl / methanol / 1 h / Heating

2: 95 percent / conc.HCl, AcOH / 3 h / Heating

With hydrogenchloride; hydroxylamine hydrochloride; acetic acid; In methanol;

Reference yield:

: 66696-98-8
tert-butyl ethyl-3-oxopentanoate

: 134541-03-0
5-Ethyl-4-isoxazolecarboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: 2 h / 60 °C

1.2: 16 h / 60 °C

2.1: acetic acid; hydrogenchloride / 16 h / Reflux

With hydrogenchloride; acetic acid;