11-(3-(4-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-1H-1,2,3-triazol-1-yl)propoxy)-N-propylnoraporphine

Base Information

Chemical Name:11-(3-(4-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-1H-1,2,3-triazol-1-yl)propoxy)-N-propylnoraporphine
CAS No.:1297273-62-1
Molecular Formula:C₃₇H₄₆N₆O₂
Molecular Weight:606.811
Hs Code.:

Synonyms:11-(3-(4-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-1H-1,2,3-triazol-1-yl)propoxy)-N-propylnoraporphine

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Chemical Property of 11-(3-(4-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-1H-1,2,3-triazol-1-yl)propoxy)-N-propylnoraporphine

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Technology Process of 11-(3-(4-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-1H-1,2,3-triazol-1-yl)propoxy)-N-propylnoraporphine

There total 4 articles about 11-(3-(4-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-1H-1,2,3-triazol-1-yl)propoxy)-N-propylnoraporphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1297273-59-6
1-(2-methoxyphenyl)-4-(but-3-yn-1-yl)-piperazine

: 1297273-51-8
C₂₂H₂₆N₄O

: 1297273-62-1
11-(3-(4-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-1H-1,2,3-triazol-1-yl)propoxy)-N-propylnoraporphine

Guidance literature:: With copper(l) iodide; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 20 ℃;
DOI:10.1016/j.bmc.2011.01.053

Reference yield:

: 1297273-53-0
C₂₂H₂₆ClNO

: 1297273-62-1
11-(3-(4-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-1H-1,2,3-triazol-1-yl)propoxy)-N-propylnoraporphine

Guidance literature:: Multi-step reaction with 2 steps

1: sodium azide / dimethyl sulfoxide / 100 °C

2: copper(l) iodide; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 20 °C

With copper(l) iodide; sodium azide; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dimethyl sulfoxide;
DOI:10.1016/j.bmc.2011.01.053

Reference yield:

: 35386-24-4
1-(2-Methoxyphenyl)piperazine

: 1297273-62-1
11-(3-(4-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-1H-1,2,3-triazol-1-yl)propoxy)-N-propylnoraporphine

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; sodium iodide / acetone / Reflux

2: copper(l) iodide; N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 20 °C

With copper(l) iodide; potassium carbonate; N-ethyl-N,N-diisopropylamine; sodium iodide; In tetrahydrofuran; acetone;
DOI:10.1016/j.bmc.2011.01.053